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Updated: May 11, 2026

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
Published on: July 11, 2013
Diagnosis and treatment of pediatric psoriasis: current and future
1Division of Dermatology, Cincinnati Children's Hospital, 3333 Burnet Avenue, MLC 3004, Cincinnati, OH 45243, USA. kara.shah@cchmc.org
Insights
Pediatric psoriasis, a complex skin condition, requires careful management. This review details current understanding and treatment options for infants, children, and adolescents with psoriasis.
Area of Science:
- Dermatology
- Pediatrics
- Immunology
Background:
- Psoriasis is a prevalent inflammatory skin disease affecting all age groups, including infants, children, and adolescents.
- Pediatric psoriasis presents with variable clinical manifestations and can pose therapeutic challenges due to limited pediatric-specific efficacy and safety data for many treatments.
Purpose of the Study:
- To provide a comprehensive overview of the pathophysiology, diagnosis, and treatment of pediatric psoriasis.
- To emphasize the available literature data on the use of various topical and systemic therapies in children.
Main Methods:
- Literature review focusing on pediatric psoriasis.
- Analysis of data on topical corticosteroids, vitamin D analogs, phototherapy, systemic immunosuppressants, and biologic agents for pediatric use.
Main Results:
- The review synthesizes current knowledge on pediatric psoriasis.
- It highlights the application and evidence base for diverse treatment modalities in managing pediatric psoriasis.
Conclusions:
- Effective management of pediatric psoriasis requires understanding its unique aspects.
- Further research is needed to establish robust efficacy and safety profiles for all treatment options in this population.
Abstract:
Psoriasis is a common yet complex inflammatory dermatosis that may be seen in infants, children, and adolescents. The clinical presentation and course may be quite variable, and while patients with mild disease are often easily managed, those with recalcitrant or more severe disease often present a therapeutic dilemma given the number of therapies available and the relative lack of data on the efficacy and safety of use of these therapies in children. This review presents the reader with an overview of the current understanding of the pathophysiology, diagnosis, and treatment of pediatric psoriasis, with an emphasis on the available data in the literature that pertains to the use in children of currently available topical and systemic therapies, including topical corticosteroids, vitamin D analogs, phototherapy, systemic immunosuppressive medications, and biologic agents.
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