Diagnosis and treatment of pediatric psoriasis: current and future

Kara N Shah1

  • 1Division of Dermatology, Cincinnati Children's Hospital, 3333 Burnet Avenue, MLC 3004, Cincinnati, OH 45243, USA. kara.shah@cchmc.org

Insights

Pediatric psoriasis, a complex skin condition, requires careful management. This review details current understanding and treatment options for infants, children, and adolescents with psoriasis.

Area of Science:

  • Dermatology
  • Pediatrics
  • Immunology

Background:

  • Psoriasis is a prevalent inflammatory skin disease affecting all age groups, including infants, children, and adolescents.
  • Pediatric psoriasis presents with variable clinical manifestations and can pose therapeutic challenges due to limited pediatric-specific efficacy and safety data for many treatments.

Purpose of the Study:

  • To provide a comprehensive overview of the pathophysiology, diagnosis, and treatment of pediatric psoriasis.
  • To emphasize the available literature data on the use of various topical and systemic therapies in children.

Main Methods:

  • Literature review focusing on pediatric psoriasis.
  • Analysis of data on topical corticosteroids, vitamin D analogs, phototherapy, systemic immunosuppressants, and biologic agents for pediatric use.

Main Results:

  • The review synthesizes current knowledge on pediatric psoriasis.
  • It highlights the application and evidence base for diverse treatment modalities in managing pediatric psoriasis.

Conclusions:

  • Effective management of pediatric psoriasis requires understanding its unique aspects.
  • Further research is needed to establish robust efficacy and safety profiles for all treatment options in this population.

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