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Profilin 1: do we have a novel proteome-found biomarker predicting response to anticancer therapy?
Proteomics
|May 17, 2013
Abstract:
About three decades ago, profilin 1 was described as a 15 kDa small protein. It was later shown that profilin 1 is a tumor suppressor in human carcinomas. Recent proteome-based data additionally demonstrated that the levels of profilin 1 expression could help to predict malignant tumor aggressiveness, response to anticancer therapy and risk of recurrence development.
