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Related Experiment Video

Updated: May 11, 2026

Treatment Model for Young Patients with Psychogenic Erectile Dysfunction and Resultant Infertility

Treatment Model for Young Patients with Psychogenic Erectile Dysfunction and Resultant Infertility

Published on: May 30, 2025

Sexual precocity and its treatment.

DeAnna B Brown¹, Lindsey A Loomba-Albrecht, Andrew A Bremer

¹Department of Pediatrics, Vanderbilt University School of Medicine, Nashville, TN 37232, USA.

World Journal of Pediatrics : WJP

|May 17, 2013

Summary

Sexual precocity, or early puberty, involves physical and psychological changes. Treatment depends on the cause, with GnRH agonists used for GnRH-dependent cases and addressing underlying issues for GnRH-independent precocious puberty.

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Determination of Reproductive Competence by Confirming Pubertal Onset and Performing a Fertility Assay in Mice and Rats

Determination of Reproductive Competence by Confirming Pubertal Onset and Performing a Fertility Assay in Mice and Rats

Published on: October 13, 2018

Area of Science:

Pediatric Endocrinology
Developmental Biology

Background:

Puberty is a complex developmental transition involving somatic growth and sexual maturation.
Sexual precocity is defined as the onset of secondary sexual characteristics before the typical age range.

Purpose of the Study:

To review the normal timing of puberty.
To define, classify, and diagnose sexual precocity.
To discuss management strategies for precocious puberty.

Main Methods:

Literature review of recent publications.
Analysis of clinical experience with sexual precocity.
Synthesis of information on pubertal development and its variations.

Main Results:

Sexual precocity is classified as GnRH-dependent or GnRH-independent.
It leads to accelerated growth, somatic development, and skeletal maturation.
Profound physical and psychological implications can arise from sexual precocity.

Conclusions:

Treatment of sexual precocity targets the underlying cause and addresses psychosocial and clinical aspects.
GnRH agonists are primary for GnRH-dependent precocious puberty.
Management of GnRH-independent sexual precocity focuses on the specific causative disorder.