Radiation exposure in extremely low birth weight infants during their neonatal intensive care unit stay

Narayan Prabhu Iyer1, Amy Baumann, Mark Stephen Rzeszotarski

  • 1Department of Pediatrics, MetroHealth Medical Center, Case Western Reserve University, Cleveland, Ohio 44109, USA.

Insights

Extremely low birth weight (ELBW) infants in the neonatal intensive care unit (NICU) receive significant diagnostic X-ray exposure. Monitoring radiation doses is crucial to prevent potential harm to these vulnerable infants.

Area of Science:

  • Neonatal care
  • Pediatric radiology
  • Medical physics

Background:

  • Extremely low birth weight (ELBW) infants (<1000 g) may exhibit heightened sensitivity to radiation.
  • Neonatal intensive care unit (NICU) stays involve diagnostic imaging procedures for ELBW infants.

Purpose of the Study:

  • To estimate the cumulative radiation exposure in surviving ELBW infants during their NICU hospitalization.
  • To identify factors associated with radiation exposure in ELBW infants.

Main Methods:

  • Retrospective cohort study analyzing medical records of ELBW infants admitted to a NICU.
  • Estimation of total entrance skin exposure (ESE) in micro-Gray (μGy) from X-ray procedures.
  • Correlation analysis between ESE and gestational age (GA), birth weight (BW), and illness severity (SNAPPE).

Main Results:

  • 450 ELBW survivors received a median of 32 X-rays, with a median ESE of 1471 μGy.
  • Total ESE was inversely correlated with GA and BW, and positively correlated with illness severity (SNAPPE).
  • Gestational age, SNAPPE, and necrotizing enterocolitis were significant predictors of radiation exposure in ELBW infants.

Conclusions:

  • ELBW infants undergo substantial diagnostic X-ray exposure during NICU care.
  • There is a critical need for vigilant monitoring of X-ray procedures in ELBW infants.
  • Minimizing unnecessary radiation exposure is essential for the well-being of ELBW infants.
Abstract

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