Related Experiment Video
Updated: May 11, 2026

Handwriting Analysis Indicates Spontaneous Dyskinesias in Neuroleptic Naïve Adolescents at High Risk for Psychosis
Published on: November 21, 2013
[Late-onset schizophrenia]
1Department of Psychiatry, Jichi Medical University.
Abstract:
We conducted clinical research at Jichi Medical University Hospital psychiatric ward on 38 patients over the age of 40 with late-onset schizophrenia and on 278 patients under the age of 40 with early-onset schizophrenia. Cases with onset after age 40 reported in 12% of the total population. Female cases were 20.4%, and the result was significantly higher than the male cases of 4.3%. Paranoid type was 55.3% of the total population of the late-onset cases, and it was significantly higher than the early-onset cases of younger than 40 years old. 55.3% of late-onset cases were combined with depressive symptoms, and they rated significantly higher than early-onset cases.
Related Concept Videos
Schizophrenia
Psychological and Sociocultural Causes of Schizophrenia
Biological Causes of Schizophrenia
Genetic Factors in Schizophrenia
The genetic basis of schizophrenia is strongly supported by family and twin studies.
Psychosis: Pathophysiology of Schizophrenia and Other Psychotic Disorders
Researchers have identified genetic factors that increase susceptibility to schizophrenia, underscoring the intricate interplay between genetics and environment in disease development. At the core of schizophrenia's pathophysiology is excessive dopaminergic neurotransmission within the...
Psychosis: Goals of Pharmacotherapy
Negative and Cognitive Symptoms of Schizophrenia
Negative Symptoms
Negative symptoms of schizophrenia manifest as deficits in normal emotional and behavioral functioning, profoundly impacting daily life. Individuals with schizophrenia often display a flat affect, characterized by a near-total absence of emotional expression,...
