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Updated: May 11, 2026

Robotic Myotomy and Partial Fundoplication for Achalasia

Robotic Myotomy and Partial Fundoplication for Achalasia

Published on: August 11, 2023

Esophageal dysmotility: characterization and pathophysiology.

A Aspirot¹, C Faure

¹Division of Pediatric Surgery, Sainte-Justine University Health Center, Montreal, Quebec, Canada H3T 1C5. ann.aspirot.hsj@ssss.gouv.qc.ca

Diseases of the Esophagus : Official Journal of the International Society for Diseases of the Esophagus

|May 18, 2013

Summary

Esophageal dysmotility is common in patients with esophageal atresia (EA). High-resolution manometry helps characterize specific motility patterns, but correlations with symptoms and long-term evolution remain unclear.

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Area of Science:

Gastroenterology
Pediatric Surgery
Developmental Biology

Background:

Esophageal dysmotility is a significant long-term complication in patients with esophageal atresia (EA).
Previous studies utilized esophageal manometry to assess motility defects in operated EA patients.
Advancements in high-resolution manometry offer improved characterization of esophageal function.

Purpose of the Study:

To review normal esophageal motility and detail specific defects in EA patients.
To characterize esophageal motility patterns in operated EA patients using high-resolution manometry.
To discuss pathophysiological hypotheses for esophageal dysmotility in EA.

Main Methods:

Review of normal esophageal motility.
Application of high-resolution manometry in patients with operated EA.
Description of identified esophageal motility patterns: aperistalsis, pressurization, and distal peristalsis.

Main Results:

Three distinct esophageal motility patterns (aperistalsis, pressurization, distal peristalsis) were identified in operated EA patients.
No correlation was found between the severity of dysmotility and patient symptomatology.
Potential contributing factors include developmental neuronal defects, surgical trauma, and esophagitis from impaired acid clearance.

Conclusions:

High-resolution manometry provides enhanced characterization of esophageal motility in EA patients.
The etiology of esophageal dysmotility in EA is multifactorial, involving congenital and acquired factors.
Further research is needed to understand the long-term evolution of esophageal dysmotility in repaired EA.