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Updated: May 11, 2026

In Vivo Infection with Leishmania amazonensis to Evaluate Parasite Virulence in Mice
Published on: February 20, 2020
Bone marrow negative visceral leishmaniasis in an adolescent male
1Department of Pathology, Hamdard Institute of Medical Sciences and Research, New Delhi, 110062, India ; Department of Medicine, Hamdard Institute of Medical Sciences and Research, New Delhi, 110062, India.
Abstract:
Visceral Leishmaniasis or Kala Azar is endemic in certain regions of India. In endemic areas, the constellation of fever, progressive weight loss, weakness, pronounced splenomegaly, anemia, leukopenia, and hypergammaglobulinemia is highly suggestive of visceral leishmaniasis. Demonstration of the parasite in liver, splenic or bone marrow aspirates is confirmatory. We present a case in which Leishmania donovani (LD) bodies were demonstrated on splenic aspirate. We were unable to demonstrate LD bodies on bone marrow aspiration.
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