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Updated: May 11, 2026

A Microfluidic-based Hydrodynamic Trap for Single Particles

A Microfluidic-based Hydrodynamic Trap for Single Particles

Published on: January 21, 2011

Manipulation and confinement of single particles using fluid flow.

Melikhan Tanyeri¹, Charles M Schroeder

¹Department of Chemical and Biomolecular Engineering, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, USA.

|May 21, 2013

Summary

Researchers developed a novel hydrodynamic flow method for precise micro- and nanoscale particle manipulation. This technique enables automated fluid flow control for high-precision positioning and manipulation of small particles in aqueous environments.

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Confocal Imaging of Confined Quiescent and Flowing Colloid-polymer Mixtures

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Published on: May 20, 2014

Area of Science:

Fluid dynamics
Nanotechnology
Microfluidics

Background:

Precise control of micro- and nanoscale objects is crucial for nanoscience.
Current particle trapping methods rely on optical, magnetic, electrokinetic, and acoustic fields.

Purpose of the Study:

To introduce a new hydrodynamic flow-based approach for micro- and nanoscale particle manipulation.
To demonstrate fine-scale manipulation and positioning of single particles using automated fluid flow.

Main Methods:

Developed a hydrodynamic flow system for particle trapping.
Utilized automated fluid flow for precise manipulation.
Demonstrated two-dimensional (2D) manipulation of particles with varying diameters.

Main Results:

Achieved high-precision positioning of 500 nm and 2.2 μm particles, with precision as small as 180 nm.
Showcased efficient control over the effective trap potential by adjusting a single flow parameter.
Demonstrated particle isolation from crowded solutions and active control of the surrounding medium.

Conclusions:

The 2D hydrodynamic flow trapping method offers a new tool for micro/nanomanipulation.
This technique shows significant promise for applications in biology, chemistry, and materials science.
The method allows for precise control and manipulation of small particles in aqueous media.