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Related Concept Videos

Hypertension III: Clinical Manifestations and Diagnostic Studies01:30

Hypertension III: Clinical Manifestations and Diagnostic Studies

Hypertension is asymptomatic and also referred to as the "silent killer" until it progresses to a severe stage or causes target organ disease. Patients may experience symptoms stemming from the strain on blood vessels and tissues in various organs or the heart's increased workload.Physical exams might show no abnormalities other than high blood pressure. Signs of vascular damage, when present, correspond to the organs supplied by the affected vessels, leading to target organ damage. For...
Hypertension I: Introduction01:28

Hypertension I: Introduction

Hypertension is a widespread, long-term medical condition where blood pressure in the arteries remains elevated. It is characterized by systolic blood pressure readings of 130 mm Hg or above or diastolic blood pressure (DBP) readings of 80 mm Hg or higher. Unmanaged hypertension poses significant health risks, making the distinction between primary (or essential) hypertension and secondary hypertension crucial, as their management and implications vary.Primary HypertensionPrimary hypertension,...
Special considerations while measuring blood pressure01:28

Special considerations while measuring blood pressure

When assessing blood pressure (BP), healthcare professionals must consider various factors and potential unexpected outcomes to ensure accurate readings and provide proper patient care. Adhering to these guidelines is essential to achieving the most reliable results.
Monitoring Both Arms:
Monitoring BP in both arms during the initial assessment is advisable, as the systolic value may differ by five to ten mm Hg between arms. For subsequent BP assessments, use the arm with the higher reading.
Alterations in Blood Pressure01:30

Alterations in Blood Pressure

Alterations in blood pressure, such as hypertension (high blood pressure) and hypotension (low blood pressure), significantly affect human health. Understanding these conditions' classifications, causes, and symptoms is essential for effective management and treatment.
Hypertension (High blood pressure)
Hypertension occurs when blood pressure readings consistently exceed the normal range. It is diagnosed when systolic blood pressure (the top number, indicating pressure while the heart beats)...
Measurement of Blood Pressure01:17

Measurement of Blood Pressure

Assessing blood pressure is a standard procedure executed in virtually all medical environments. The method utilized today was established over a hundred years ago by an innovative Russian doctor, Dr. Nikolai Korotkoff. The soft ticking noise, known as Korotkoff sounds, heard while taking blood pressure readings results from turbulent blood flow within the vessels. The apparatus required for this procedure includes a sphygmomanometer, a blood pressure cuff attached to a gauge, and a stethoscope.
Hypertension II: Pathophysiology01:29

Hypertension II: Pathophysiology

Hypertension is a chronic condition in which the blood's force against artery walls is excessively high, posing risks such as heart disease. The condition's underlying mechanisms involve complex interactions among the cardiovascular, kidney, and autonomic nervous systems.Renin-Angiotensin-Aldosterone System (RAAS): This system significantly influences blood pressure regulation. When blood pressure decreases, the kidneys secrete renin. This enzyme transforms angiotensinogen, a plasma protein,...

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Related Experiment Video

Updated: May 11, 2026

Tilt Testing with Combined Lower Body Negative Pressure: a "Gold Standard" for Measuring Orthostatic Tolerance
14:09

Tilt Testing with Combined Lower Body Negative Pressure: a "Gold Standard" for Measuring Orthostatic Tolerance

Published on: March 21, 2013

White-coat hypertension.

Catherine A Martin1, Barry P McGrath

  • 1Monash University, Melbourne, Vic., Australia; Monash Health, Melbourne, Vic., Australia; Australian Catholic University, Melbourne, Vic., Australia.

Clinical and Experimental Pharmacology & Physiology
|May 21, 2013
PubMed
Summary
This summary is machine-generated.

White-coat hypertension (WCHT), affecting 15% of the population, is linked to higher cardiovascular risks. Management should prioritize metabolic factors like glucose intolerance over solely focusing on blood pressure.

Keywords:
cardiovascular riskglucose intoleranceisolated clinic hypertensionwhite-coat hypertension

Related Experiment Videos

Last Updated: May 11, 2026

Tilt Testing with Combined Lower Body Negative Pressure: a "Gold Standard" for Measuring Orthostatic Tolerance
14:09

Tilt Testing with Combined Lower Body Negative Pressure: a "Gold Standard" for Measuring Orthostatic Tolerance

Published on: March 21, 2013

Area of Science:

  • Cardiology
  • Hypertension Research
  • Preventive Medicine

Background:

  • White-coat hypertension (WCHT) definitions have lacked robustness, leading to inconsistent findings on its cardiovascular risk.
  • International guidelines offer a standardized definition for WCHT, crucial for accurate risk assessment.

Purpose of the Study:

  • To review and standardize evidence on WCHT by including studies adhering to international guidelines.
  • To clarify the association between WCHT and cardiovascular risk, vascular dysfunction, and target organ damage.

Main Methods:

  • Systematic review of published studies meeting standardized WCHT criteria.
  • Analysis of data concerning vascular dysfunction, target organ damage, and future cardiovascular events.

Main Results:

  • WCHT affects approximately 15% of the population and is associated with elevated clinic blood pressure and non-smoking status.
  • Individuals with WCHT exhibit increased cardiovascular risk, characterized by higher glucose dysregulation, increased left ventricular mass index, and elevated risk for diabetes and sustained hypertension.

Conclusions:

  • WCHT is associated with significant cardiovascular risks beyond elevated clinic blood pressure.
  • Patient management for WCHT should emphasize addressing cardiovascular risk factors, particularly glucose intolerance, rather than focusing exclusively on blood pressure control.