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Related Experiment Video

Updated: May 11, 2026

Autonomous and Rechargeable Microneurostimulator Endoscopically Implantable into the Submucosa

Autonomous and Rechargeable Microneurostimulator Endoscopically Implantable into the Submucosa

Published on: September 27, 2018

An implantable neural interface with electromagnetic stimulation capabilities.

D Accoto¹, M T Francomano, A Rainer

¹CIR-Laboratory of Biomedical Robotics and Biomicrosystems, Università Campus Bio-Medico di Roma, Via Alvaro del Portillo 21, 00128 Rome, Italy. d.accoto@unicampus.it

Medical Hypotheses

|May 21, 2013

Summary

This summary is machine-generated.

This study introduces novel electromagnetic neural interfaces to overcome fibrosis for improved prosthetic and assistive technologies. The technology uses electromagnetic waves and nanoparticles for enhanced nerve stimulation and signal recording.

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Implantation and Control of Wireless, Battery-free Systems for Peripheral Nerve Interfacing

Implantation and Control of Wireless, Battery-free Systems for Peripheral Nerve Interfacing

Published on: October 20, 2021

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Last Updated: May 11, 2026

Autonomous and Rechargeable Microneurostimulator Endoscopically Implantable into the Submucosa

Autonomous and Rechargeable Microneurostimulator Endoscopically Implantable into the Submucosa

Published on: September 27, 2018

Implantation and Control of Wireless, Battery-free Systems for Peripheral Nerve Interfacing

Implantation and Control of Wireless, Battery-free Systems for Peripheral Nerve Interfacing

Published on: October 20, 2021

Area of Science:

Biomedical Engineering
Neuroscience
Materials Science

Background:

Invasive neural interfaces are crucial for prosthetics and assistive technologies.
Current electrical interfaces face signal-to-noise ratio degradation due to fibrosis.
Peripheral Nervous System (PNS) interfaces require advanced solutions.

Purpose of the Study:

To propose a novel implantable neural interface concept utilizing electromagnetic (EM) stimulation.
To overcome the challenge of fibrosis in neural interfaces.
To enhance nerve signal recording and stimulation selectivity.

Main Methods:

Development of microfabricated coils for in situ EM wave generation.
Integration of stimulation coils and recording electrodes on a flexible substrate.
Application of a bio-absorbable coating releasing anti-fibrotic drugs and functionalized magnetic nanoparticles (NPs).

Main Results:

The proposed EM approach aims to penetrate fibrotic capsules effectively.
Functionalized NPs are designed to enhance EM wave-induced nerve depolarization.
Preliminary in silico feasibility study conducted to validate the concept.

Conclusions:

The novel electromagnetic interface offers a promising alternative to overcome fibrosis in neural implants.
The combination of EM stimulation, drug release, and NPs enhances interface performance.
Further research and development are warranted for clinical translation.