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Updated: May 11, 2026

Characterization of Vascular Morphology of Neovascular Age-Related Macular Degeneration by Indocyanine Green Angiography
Published on: August 11, 2023
Indocyanine green angiography in posterior uveitis
Rupesh V Agrawal1, Jyotirmay Biswas, Dinesh Gunasekaran
1Department of Ophthalmology, National Healthcare Group Eye Institute, Tan Tock Seng Hospital, Singapore.
Indocyanine green angiography (ICGA) aids in diagnosing posterior uveitis by revealing characteristic hypofluorescent spots. While not replacing fluorescein angiography, ICGA offers valuable complementary information for inflammatory chorioretinal diseases.
Area of Science:
- Ophthalmology
- Medical Imaging
- Inflammatory Diseases
Background:
- Posterior uveitis encompasses diverse inflammatory chorioretinal conditions.
- Accurate diagnosis is crucial for effective management and visual preservation.
- Established imaging modalities like fluorescein angiography have limitations in certain cases.
Purpose of the Study:
- To evaluate the diagnostic role of indocyanine green angiography (ICGA) in posterior uveitis.
- To review the literature and analyze ICGA findings in various posterior uveitis subtypes.
- To assess ICGA as an adjunctive tool for diagnosing inflammatory chorioretinal disorders.
Main Methods:
- Comprehensive literature review on ICGA in uveitis.
- Retrospective analysis of medical records for patients with posterior uveitis.
- Inclusion of patients who underwent both fundus examination and ICGA.
Main Results:
- ICGA demonstrated characteristic hypofluorescent dark spots in various posterior uveitis types.
- Specific patterns were observed in serpiginous choroiditis, ampiginous choroiditis, and other conditions.
- ICGA provided additional diagnostic information beyond standard fundus examination.
Conclusions:
- Indocyanine green angiography is a valuable adjunctive tool for diagnosing inflammatory chorioretinal diseases.
- ICGA complements fluorescein angiography by offering unique insights into choroidal inflammation.
- Further research is needed to determine ICGA's utility in monitoring disease progression.
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