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Updated: May 11, 2026

A Bioluminescent and Fluorescent Orthotopic Syngeneic Murine Model of Androgen-dependent and Castration-resistant Prostate Cancer
Published on: March 6, 2018
Prolonged hypocalcemia following denosumab therapy in metastatic hormone refractory prostate cancer
1Department of Endocrinology, Monash Health, Monash Medical Centre, Clayton, Australia. fran.milat@princehenrys.org
Abstract:
Prostate cancer is a leading cause of cancer death, frequently associated with widespread bone metastases. We report two cases of hypocalcemia following the first dose of denosumab in metastatic hormone refractory prostate cancer, the first case requiring 26 days of intravenous calcium therapy. This is the first report of prolonged hypocalcemia following denosumab in a patient with normal renal function.
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