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Mizoroki-Heck Cross-coupling Reactions Catalyzed by Dichloro{bis[1,1',1''-(phosphinetriyl)tripiperidine]}palladium Under Mild Reaction Conditions
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Efficient catalysts for asymmetric Mannich reactions

Michał Rachwalski1, Tim Leenders, Sylwia Kaczmarczyk

  • 1Radboud University Nijmegen, Institute for Molecules and Materials, Heyendaalseweg 135, 6525 AJ Nijmegen, The Netherlands. m.rachwalski@science.ru.nl

Organic & Biomolecular Chemistry
|May 21, 2013
PubMed
Summary

New chiral catalysts enable efficient asymmetric Mannich reactions, yielding valuable beta-amino carbonyl compounds with high selectivity. Optimization using ultrasonication improved results.

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