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Related Experiment Videos

[Insufficient accommodation in patient with keratoconus].

G Ohmi1, S Kinoshita, M Matsuda

  • 1Dept. of Ophthalmol. Osaka Univ. Medical School, Japan.

Nippon Ganka Gakkai Zasshi
|February 1, 1990
PubMed
Summary

Patients with keratoconus exhibit significantly reduced accommodation amplitude and pupillary constriction. These findings suggest underlying iris and ciliary body abnormalities in keratoconus.

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Area of Science:

  • Ophthalmology
  • Corneal Diseases
  • Neuro-ophthalmology

Context:

  • Keratoconus is a progressive corneal disease affecting visual function.
  • Accommodation and pupillary responses are crucial for clear vision at varying distances.
  • Previous research has not fully elucidated the accommodative and pupillary function in unoperated keratoconus patients.

Purpose:

  • To investigate and compare the accommodation response and pupillary dynamics between patients with keratoconus and healthy controls.
  • To assess potential correlations between these functional parameters and keratoconus severity.

Summary:

  • This study measured quasistatic accommodation amplitude and pupillary response in 10 unoperated keratoconus patients and 10 age-matched controls using an infrared high-speed optometer and iriscorder.

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  • Results showed significantly lower accommodation amplitude (2.8 D vs. 4.7 D) and reduced maximum pupillary constriction (0.25 vs. 0.56) in the keratoconus group.
  • No significant correlation was found between these functional deficits and the severity of keratoconus.

    • Impact:

    • The findings indicate potential pre-existing abnormalities in the iris and ciliary body in keratoconus patients.
    • These abnormalities may contribute to the paretic pupil phenomenon observed post-keratoplasty in some keratoconus cases.
    • This research highlights the need for further investigation into the ocular motor system in keratoconus.