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Application of Genetically Encoded Fluorescent Nitric Oxide (NO•) Probes, the geNOps, for Real-time Imaging of NO• Signals in Single Cells
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Application of Genetically Encoded Fluorescent Nitric Oxide (NO•) Probes, the geNOps, for Real-time Imaging of NO• Signals in Single Cells

Published on: March 16, 2017

A new strategy for the design of molecular probes for investigating endogenous nitric oxide using an EPR or

Y Katayama1, N Soh, M Maeda

  • 1Department of Applied Chemistry, Faculty of Engineering, Kyushu University, Higashi-ku, Fukuoka, Japan. ykatatcm@mbox.nc.kyushu-u.ac.jp

Chemphyschem : a European Journal of Chemical Physics and Physical Chemistry
|May 21, 2013
PubMed

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Labeling DNA Probes03:31

Labeling DNA Probes

DNA probes are fragments of DNA labeled with a reporter tag to enable their detection or purification. The resulting labeled DNA probes can then hybridize to target nucleic acid sequences through complementary base-pairing, and may be used to recover or identify these regions.
Radioisotopes, fluorophores, or small molecule binding partners like biotin or digoxigenin, are the most widely used reporter tags for labeling DNA probes. These labels can be attached to the probe DNA molecule via...