Nonrelevant cerebral atherosclerosis is a strong prognostic factor in acute cerebral infarction
Jinkwon Kim1, Tae-Jin Song, Dongbeom Song
1Department of Neurology, CHA Bundang Medical Center, CHA University, Seongnam, Republic of Korea.
Background And Purpose:
We investigated whether the presence of nonrelevant cerebral atherosclerosis (NRCA) had prognostic value in patients with acute stroke.
Methods:
We compared prognosis in 780 consecutive patients with first-ever acute cerebral infarction who underwent cerebral angiography and diffusion-weighted MRI.
Results:
NRCA was present in 267 patients (34.2%). Multivariate analysis demonstrated that the presence of NRCA was independently associated with less improvement in National Institute of Health Stroke Scale score during the first 7 days (P=0.004), and a poor functional outcome (modified Rankin Scale score >2) after 3 months (odds ratio, 2.51; 95% confidence interval, 1.55-4.07). An increase in burden count of NRCA was also associated with poor outcomes.
Conclusions:
The presence and burden count of NRCA were associated with poor neurological outcomes in patients with acute cerebral infarction.
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