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Published on: February 26, 2013
Arrhythmic complications after electrical cardioversion of acute atrial fibrillation: the FinCV study
Toni Grönberg1, Ilpo Nuotio, Marko Nikkinen
1Heart Center, Turku University Hospital, Kiinamyllynkatu 4-8, FIN-20520 Turku, Finland.
Insights
Bradycardic complications following electrical cardioversion for acute atrial fibrillation (AF) are rare and typically benign. However, older age, female sex, and unsuccessful cardioversion increase the risk, sometimes necessitating permanent pacemaker implantation.
Area of Science:
- Cardiology
- Electrophysiology
- Internal Medicine
Background:
- Atrial fibrillation (AF) is a common arrhythmia requiring treatment.
- Electrical cardioversion is a standard procedure for acute AF.
- Arrhythmic complications, particularly bradycardia, can occur post-cardioversion.
Purpose of the Study:
- To determine the incidence of arrhythmic complications after electrical cardioversion of acute AF.
- To identify risk factors associated with these complications.
- To assess the need for permanent pacemaker implantation following bradycardic events.
Main Methods:
- Retrospective multicenter study analyzing 7660 cardioversions of acute AF (<48 hours).
- Data collected from 3143 consecutive patients.
- Evaluation of immediate arrhythmic complications and predictors.
Main Results:
- Bradyarrhythmia occurred in 0.9% of cardioversions (63 cases).
- Asystole was observed in 51 instances, with 2 requiring extrinsic pacing.
- Independent predictors of bradycardic complications included older age, female sex, and unsuccessful cardioversion.
Conclusions:
- Bradycardic complications are infrequent and generally benign after acute AF cardioversion.
- These events may indicate underlying sinus node dysfunction.
- A significant proportion of patients experiencing bradycardia ultimately require permanent pacemaker implantation.
Aims:
To determine the incidence and risk factors of arrhythmic complications after electrical cardioversion of acute atrial fibrillation (AF).
Methods And Results:
Our retrospective multicentre study collected data from 7660 cardioversions of acute (<48 h) AF in 3143 consecutive patients. Immediate arrhythmic complications were evaluated after 6906 (90.2%) electrical cardioversions performed in 2868 patients. We also assessed the predictors of arrhythmic complications and whether post-cardioversion bradycardia or asystole led to later a permanent pacemaker implantation. Altogether, 63 (0.9%) electrical cardioversions resulted in bradyarrhythmia in 54 patients. Asystole (>5 s) occurred immediately after 51 cardioversions leading to a short resuscitation in seven cases and two patients needed extrinsic pacing after the cardioversion. In nine cases, asystole was followed by bradycardia. Bradycardic ventricular rate (<40 b.p.m.) alone was seen after 12 procedures. No ventricular arrhythmias needing intervention were detected. Old age [odds ratio (OR) 1.1; 95% confidence interval (CI) 1.05-1.10, P < 0.0001], female sex (OR 2.5; 95% CI 1.4-4.8, P = 0.004), and unsuccessful cardioversion (OR 2.2; 95% CI 1.1-4.6, P = 0.03) were the independent predictors of bradycardic complications. Slow ventricular rate, use of digoxin, beta blocker, or antiarrhythmic medication did not increase the risk of bradycardic complications. Pacemaker was implanted in 24 (44.4%) patients after a median delay of 66 days.
Conclusion:
Bradycardic complications are rare and usually benign after cardioversion of acute AF. They seem to reflect sinus node dysfunction and often result in later implantation of a permanent pacemaker.
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