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Updated: May 11, 2026

Iridium(III) Luminescent Probe for Detection of the Malarial Protein Biomarker Histidine Rich Protein-II
Published on: July 7, 2015
Turn-on selective vitamin B6 derivative fluorescent probe for histidine detection in biological samples
Elisabete Oliveira1, Carla Santos, Patrícia Poeta
1BIOSCOPE group, REQUIMTE-CQFB, Chemistry Department, Faculty of Science and Technology, University NOVA of Lisbon, 2829-516, Monte de Caparica, Portugal. ejo14209@fct.unl.pt
Abstract:
A new compound L soluble in water derived from vitamin B6 was successfully synthesized and characterized. The complex LAl(3+) is a turn-on selective fluorescent probe for histidine in HEPES buffer, with detection and quantification limits of 0.3 μM and 0.6 μM, respectively. The application of the complex LAl(3+) in real urine samples is reported.
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