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Updated: May 11, 2026

A Model for Epilepsy of Infectious Etiology using Theiler's Murine Encephalomyelitis Virus

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Published on: June 23, 2022

Schmallenberg virus.

K Wernike¹, B Hoffmann, M Beer

¹Institute of Diagnostic Virology, Friedrich-Loeffler-Institut (FLI), Greifswald-Insel Riems, Germany.

Developments in Biologicals

|May 22, 2013

Summary

This summary is machine-generated.

Schmallenberg virus (SBV), a novel Orthobunyavirus, emerged in Europe in 2011. While adult ruminants show mild symptoms, SBV infection during pregnancy causes severe fetal malformations, necessitating ongoing research and diagnostics.

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Area of Science:

Veterinary Virology
Emerging Infectious Diseases
Ruminant Health

Background:

A novel Simbu serogroup virus, Schmallenberg virus (SBV), was identified in 2011.
SBV rapidly disseminated across Europe, with biting midges implicated in its transmission.
Adult ruminants exhibit mild or asymptomatic infections, but pregnant animals are at risk.

Purpose of the Study:

To summarize the emergence and characteristics of Schmallenberg virus.
To highlight the clinical impact of SBV on ruminant reproduction.
To underscore the importance of diagnostic development and continued research.

Main Methods:

Surveillance and identification of the novel virus.
Epidemiological investigations into transmission vectors.
Clinical and pathological examinations of affected animals.
Development of diagnostic tools (real-time RT-PCR, ELISA).

Main Results:

Schmallenberg virus (SBV) emerged in Europe in late 2011.
SBV causes arthrogryposis-hydranencephaly syndrome in offspring of infected pregnant ruminants.
Diagnostic assays are now available, and significant knowledge has been acquired.

Conclusions:

Schmallenberg virus poses a significant threat to ruminant reproduction.
Continued research and information exchange are crucial for managing SBV.
Available diagnostic tools aid in surveillance and control efforts.