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Advanced Animal Model of Colorectal Metastasis in Liver: Imaging Techniques and Properties of Metastatic Clones
Published on: November 30, 2016
The ALPPS technique for bilateral colorectal metastases: three "variations on a theme"
Riccardo Gauzolino1, Marion Castagnet, Marie Laure Blanleuil
1University Hospital, Poitiers, France. Riccardo.GAUZOLINO@chu-poitiers.fr
Updates in Surgery
|May 22, 2013
Summary
The associating liver partition and portal vein ligation for staged hepatectomy (ALPPS) technique, including its classic and modified forms, is feasible for selected patients with liver metastases. This approach offers a viable alternative to traditional two-stage hepatectomy.
Area of Science:
- Hepatobiliary surgery
- Surgical oncology
- Liver transplantation
Background:
- The associating liver partition and portal vein ligation for staged hepatectomy (ALPPS) is a complex procedure for managing extensive liver tumors.
- Technical variations of ALPPS aim to improve outcomes and expand its applicability.
Purpose of the Study:
- To evaluate the feasibility of three technical variations of the ALPPS technique.
- To assess the safety and efficacy of these modified ALPPS approaches.
Main Methods:
- The study included four patients with colorectal metastases undergoing ALPPS.
- Variations included classic ALPPS, "left ALPPS," "rescue ALPPS," and "right ALPPS."
- Liver splitting techniques and portal vein ligation strategies were analyzed.
Main Results:
- No postoperative mortality was observed.
- Morbidity included two Clavien-Dindo grade I events and one grade IIIb event.
- Median follow-up was 4 months, with all patients alive.
Conclusions:
- The ALPPS technique, in its classic and modified forms, is a feasible option for selected patients with bilateral colorectal metastases.
- Modified ALPPS approaches offer a viable alternative to conventional two-stage hepatectomy.
