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Spontaneous coronary artery dissection: is there a metabolic association?

J J Liang1, J H Skalski, R Mankad

  • 1Department of Internal Medicine, Mayo Clinic, Rochester, MN 55905, USA.

Perfusion
|May 22, 2013
PubMed

Insights

Spontaneous coronary artery dissection (SCAD) is rare, typically affecting young women. This case highlights a man with multivessel SCAD and hyperhomocysteinemia, suggesting a potential link between these conditions.

Area of Science:

  • Cardiology
  • Internal Medicine
  • Genetics

Background:

  • Spontaneous coronary artery dissection (SCAD) is an uncommon cause of acute myocardial infarction, often presenting in young women without traditional cardiovascular risk factors.
  • Hyperhomocysteinemia, an elevated level of homocysteine in the blood, is a known risk factor for various cardiovascular diseases.

Observation:

  • A male patient presented with chest pain and arrhythmia.
  • Diagnostic imaging revealed multivessel spontaneous coronary artery dissection.
  • Laboratory tests identified hyperhomocysteinemia in the patient.

Findings:

  • The case demonstrates a rare occurrence of multivessel SCAD in a male patient.
  • The co-existence of SCAD and hyperhomocysteinemia in this patient suggests a potential association.
  • This finding challenges the classical demographic profile of SCAD patients.

Implications:

  • Further research is warranted to explore the potential link between hyperhomocysteinemia and SCAD.
  • This case may broaden the understanding of SCAD etiology and risk factors.
  • Consideration of hyperhomocysteinemia screening in select SCAD patients may be beneficial.

Keywords:
acute coronary syndromehomocysteinehyperhomocysteinemiaspontaneous coronary artery dissectionventricular tachycardia

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