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Gross Anatomy of the Liver

Gross Anatomy of the Liver

The liver, the largest gland within the human body, is a firm and reddish-brown organ. This wedge-shaped structure weighs approximately 1.5 kg and occupies a significant portion of the right hypochondriac and epigastric regions. It extends more to the right of the body's midline than to the left.
Located under the diaphragm, the liver is almost entirely ensconced within the rib cage, providing it with substantial protection. Except for the superior most bare area, the liver's surface is covered...

Liver Histology

Liver Histology

The microscopic anatomy of the liver is a complex and intricate system that comprises numerous structural units known as liver lobules, each of which is comparable in size to a sesame seed. These hexagonal structures consist of plates of liver cells or hepatocytes, which are characterized by their versatility and abundance of cellular apparatus like rough and smooth ER, Golgi apparatus, peroxisomes, and mitochondria.
Hepatocytes perform a variety of essential functions. They secrete...

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Related Experiment Video

Updated: May 11, 2026

Construction of a Preclinical Multimodality Phantom Using Tissue-mimicking Materials for Quality Assurance in Tumor Size Measurement

Construction of a Preclinical Multimodality Phantom Using Tissue-mimicking Materials for Quality Assurance in Tumor Size Measurement

Published on: July 29, 2013

Multimodal phantom of liver tissue.

Magdalena K Chmarra¹, Rune Hansen, Ronald Mårvik

¹Department of Circulation and Medical Imaging, Faculty of Medicine, Norwegian University of Science and Technology, Trondheim, Norway. mchmarra@gmail.com

|May 22, 2013

Summary

Researchers developed a cost-effective, multimodal liver phantom for medical imaging research. This patient-safe phantom accurately simulates liver tissue and structures for ultrasound, computed tomography, and magnetic resonance imaging.

Related Experiment Videos

Last Updated: May 11, 2026

Construction of a Preclinical Multimodality Phantom Using Tissue-mimicking Materials for Quality Assurance in Tumor Size Measurement

Construction of a Preclinical Multimodality Phantom Using Tissue-mimicking Materials for Quality Assurance in Tumor Size Measurement

Published on: July 29, 2013

Area of Science:

Medical Imaging
Biomedical Engineering
Radiology

Background:

Medical imaging is crucial for patient care and disease management.
Advancements in imaging technology necessitate further research.
Patient-safe and environmentally friendly research methods, such as using phantoms, are essential.

Purpose of the Study:

To develop a protocol for manufacturing a multimodal liver phantom.
To create a phantom suitable for ultrasound, computed tomography (CT), and magnetic resonance imaging (MRI).
To ensure the phantom is cost-effective, quick to produce, and reusable.

Main Methods:

Developed a phantom mimicking liver parenchyma, tumors, and portal veins.
Utilized six ingredients: candle gel, sephadex®, agarose, glycerol, distilled water, and silicone string.
The manufacturing process took approximately 2 days.

Main Results:

The developed phantom is suitable for ultrasound, CT, and MRI modalities.
Ultrasound image comparison demonstrated that the phantom's liver tissue and structures are well simulated.
The phantom preparation is simple, cost-effective, and reasonably quick.

Conclusions:

The developed multimodal liver phantom serves as a valuable tool for medical imaging research.
The phantom offers a patient-safe and environmentally friendly alternative for studying imaging techniques.
The cost-effectiveness and reusability of the phantom enhance its utility for further research and development.