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Updated: May 11, 2026

Percutaneous Hepatic Perfusion (PHP) with Melphalan as a Treatment for Unresectable Metastases Confined to the Liver
Published on: July 31, 2016
Modern prospection for hepatic arterial infusion chemotherapy in malignancies with liver metastases
Yi-Hsin Liang1, Yu-Yun Shao, Jia-Yi Chen
1Department of Hemato-Oncology, E-Da Hospital, No. 1, Yi-da Road, Jiaosu Village, Yanchao, Kaohsiung 82445, Taiwan ; Department of Oncology, National Taiwan University Hospital, No. 7, Chung-Shan South Road, Taipei City 10002, Taiwan.
Abstract:
Malignancy with liver metastasis plays an important role in daily oncology practice, especially for primary cancers of the gastrointestinal tract and hepatopancreatobiliary system. On account of the dual vascular supply system and the fact that most metastatic liver tumors are supplied by the hepatic artery, hepatic artery infusion chemotherapy (HAIC) is an appealing method for the treatment of liver metastases. Herein, we summarize recent study results reported in the literature regarding the use of HAIC for metastatic liver tumors, with special focus on colorectal cancer.

