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Related Experiment Video

Updated: May 11, 2026

Investigating the Protective Effects of Platycodin D on Non-Alcoholic Fatty Liver Disease in a Palmitic Acid-Induced In Vitro Model

Investigating the Protective Effects of Platycodin D on Non-Alcoholic Fatty Liver Disease in a Palmitic Acid-Induced In Vitro Model

Published on: December 2, 2022

[Toxic hepatitis induced by Polygonum multiflorum].

A Banarova¹, T Koller, J Payer

¹Interna klinika Lekdrskej fakulty UK a UN Bratislava, Slovenska republika. adriana.banarova@gmail.com

Vnitrni Lekarstvi

|May 23, 2013

Summary

This summary is machine-generated.

Polygonum multiflorum, a Chinese herb, can cause toxic hepatitis. Caution is advised when using herbal supplements due to potential liver injury.

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Last Updated: May 11, 2026

Investigating the Protective Effects of Platycodin D on Non-Alcoholic Fatty Liver Disease in a Palmitic Acid-Induced In Vitro Model

Investigating the Protective Effects of Platycodin D on Non-Alcoholic Fatty Liver Disease in a Palmitic Acid-Induced In Vitro Model

Published on: December 2, 2022

Area of Science:

Hepatology
Toxicology
Integrative Medicine

Background:

Acute hepatitis is frequently caused by toxic liver injury.
Herbal products are increasingly used as dietary supplements.
Polygonum multiflorum is a traditional Chinese plant with growing popularity.

Observation:

A 33-year-old female presented with nausea and jaundice, indicative of hepatocellular damage.
The patient had been consuming Polygonum multiflorum pills for two months.
Other potential causes of liver injury were ruled out.

Findings:

The patient exhibited significant hepatocellular damage linked to Polygonum multiflorum ingestion.
Causality was confirmed by rapid recovery upon discontinuation of the herb.
The case aligns with the international scoring system for drug-induced hepatotoxicity and existing literature.

Implications:

This case highlights the potential hepatotoxicity of Polygonum multiflorum.
Healthcare providers should be aware of the risks associated with herbal supplements.
Increased vigilance and patient counseling are necessary regarding the use of Polygonum multiflorum.