Inflammatory linear verrucous epidermal nevus: why a combined laser therapy

Area of Science:

• Dermatology
• Laser Therapy
• Cutaneous Hamartomas

Background:

• Inflammatory linear verrucous epidermal nevus (ILVEN) is an uncommon variant of verrucous epidermal nevus.
• ILVEN presents as a benign cutaneous hamartoma.
• Treatment resistance is common in ILVEN cases.

Observation:

• A case report details a female patient with ILVEN resistant to prior treatments.
• The patient underwent combined laser therapy using 10,600-nm CO2 laser and Fractional CO2 laser.
• Good and long-standing results were observed, with complete lesion resolution at 9 months.

Findings:

• Combined 10,600-nm CO2 pulsed laser and Fractional CO2 laser therapy demonstrated efficacy in treating ILVEN.
• Fractional CO2 laser showed promise in minimizing pigmentary changes and improving skin texture post-treatment.
• The combined approach yielded significant and lasting results for ILVEN.

Implications:

• This combined laser therapy approach offers a new, effective treatment option for ILVEN.
• The findings suggest potential for cosmetic improvement alongside lesion resolution.
• Further research into laser modalities for ILVEN management is warranted.