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[Evaluation of factors associated with tuberculosis treatment default in Chad]
N Ndeikoundam Ngangro1, D Ngarhounoum, M N Ngangro
1INSERM UMRS 707, Université Pierre et Marie Curie-Paris 6, UMRS 707, 27 rue Chaligny, Paris, France. ndeindo@hotmail.fr
Introduction:
Tuberculosis (TB) treatment default contributes to the perpetuation of the epidemic and increases the risk of emergence of new forms of multidrug-resistant TB. The aim of this study was to identify the factors associated with treatment default in Chad.
Method:
This prospective study interviewed 286 patients with pulmonary TB in three centers, recruited at the beginning of treatment. We compared patients who completed the treatment to the treatment defaulters. A logistic regression model was fit to identify factors associated with default.
Result:
32% of patients defaulted, that is, abandoned treatment. The multivariate analysis demonstrated that a low educational level and ignorance of the contagious nature of TB were associated with treatment interruption.
Conclusion:
TB education, patient assistance, and active tracing of patients who fail to return can help to prevent abandonment of TB treatment.
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