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Related Concept Videos

Skin Cancer01:30

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Skin Diseases and Disorders01:23

Skin Diseases and Disorders

Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...

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Related Experiment Video

Updated: May 11, 2026

Isolating Human Peripheral Blood Mononuclear Cells and CD4+ T cells from Sézary Syndrome Patients for Transcriptomic Profiling
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Isolating Human Peripheral Blood Mononuclear Cells and CD4+ T cells from Sézary Syndrome Patients for Transcriptomic Profiling

Published on: October 14, 2021

Current concepts on cutaneous MALT lymphomas.

Angel Fernandez-Flores1

  • 1Department of Anatomic Pathology, Hospital El Bierzo, Ponferrada, Spain. gpyauflowerlion@terra.es

The American Journal of Dermatopathology
|May 23, 2013
PubMed
Summary
This summary is machine-generated.

Understanding cutaneous mucosa-associated lymphoid tissue lymphomas has evolved significantly. This review clarifies concepts on marginal-zone cells, aiding comprehension of these complex skin lymphomas.

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Tumor Engraftment in a Xenograft Mouse Model of Human Mantle Cell Lymphoma
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Tumor Engraftment in a Xenograft Mouse Model of Human Mantle Cell Lymphoma

Published on: March 30, 2018

Related Experiment Videos

Last Updated: May 11, 2026

Isolating Human Peripheral Blood Mononuclear Cells and CD4+ T cells from Sézary Syndrome Patients for Transcriptomic Profiling
09:08

Isolating Human Peripheral Blood Mononuclear Cells and CD4+ T cells from Sézary Syndrome Patients for Transcriptomic Profiling

Published on: October 14, 2021

Tumor Engraftment in a Xenograft Mouse Model of Human Mantle Cell Lymphoma
10:52

Tumor Engraftment in a Xenograft Mouse Model of Human Mantle Cell Lymphoma

Published on: March 30, 2018

Area of Science:

  • Dermatopathology
  • Hematology
  • Oncology

Background:

  • Cutaneous mucosa-associated lymphoid tissue (MALT) lymphomas represent a dynamic area in dermatopathology.
  • Classifications have evolved from older concepts like immunocytoma.
  • Understanding their development from chronic stimulation and genetic alterations is advancing.

Purpose of the Study:

  • To provide clarity on the concepts of marginal-zone cells in cutaneous MALT lymphomas.
  • To enhance the understanding of the evolving classification and pathogenesis of these lymphomas.

Main Methods:

  • Review of recent literature and advancements in the classification of cutaneous MALT lymphomas.
  • Analysis of the role of marginal-zone cells in the evolution of these lymphomas.

Main Results:

  • The classification of cutaneous MALT lymphomas has been significantly refined.
  • New insights into the chronic stimulation and genetic basis of these lymphomas have emerged.
  • Several distinct types of cutaneous MALT lymphomas are now recognized.

Conclusions:

  • Clarifying marginal-zone cell concepts is crucial for a deeper understanding of cutaneous MALT lymphomas.
  • This understanding aids in diagnosing and managing these complex skin cancers.