Related Experiment Video

Updated: May 11, 2026

Visualization of IL-22-expressing Lymphocytes Using Reporter Mice
10:30

Visualization of IL-22-expressing Lymphocytes Using Reporter Mice

Published on: January 25, 2017

IL-22-producing CD4+ cells are depleted in actively inflamed colitis tissue

J M Leung1, M Davenport2, M J Wolff3

  • 1Division of Parasitology, Department of Microbiology, New York University School of Medicine, New York, New York, USA.

Mucosal Immunology
|May 23, 2013
PubMed
Summary

In inflammatory bowel diseases (IBD), T helper 17 (Th17) cells play a role. Ulcerative colitis (UC) patients show reduced IL-22+ cells, linked to increased TGF-β and altered gut microbiota.

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