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Site-specific organization of gold nanoparticles by biomolecular templating

S R Hall1, W Shenton, H Engelhardt

  • 1School of Chemistry, University of Bristol, Bristol BS8 1TS, UK.

Chemphyschem : a European Journal of Chemical Physics and Physical Chemistry
|May 23, 2013
PubMed
Abstract

No abstract available in PubMed .

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Immunoelectron microscopy utilizes immunogold labeling of endogenous proteins with specific antibodies to detect and localize these proteins in cells and tissues. The procedure provides insights into the distribution and quantification of protein under different stimulation conditions offering clues about their functions. Conjugating highly electron-dense gold particles with primary or secondary antibodies allow antigen detection on and within cells, with high resolution and specificity.

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