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Updated: May 11, 2026

Qualitative Identification of Carboxylic Acids, Boronic Acids, and Amines Using Cruciform Fluorophores
Published on: August 19, 2013
[Fluorescence fingerprint--a novel tool of quality control of chemical reagents]
Jing Wu1, Chao-Bo Xie, Zhi-Ping Cao
1Environmental Simulation and Pollution Control State Key Joint Laboratory, School of Environment, Tsinghua University, Beijing 100084, China. wu_jing@mail.tsinghua.edu.cn
Abstract:
Product quality control is crucial for industrial production, but there is lack of simple and effective detect methods. In this study, the chromatographically pure N-hexane from different manufacturers and same manufacturers with different batches was detected with fluorescence fingerprint technology. The results showed that the fluorescence fingerprints of all samples were different from each other. The numbers of fluorescence peaks of the fingerprints of the famous international manufacturer was stable and the intensity was low. The chromatographically pure N-hexane made in China generally had more peaks, higher intensities and greater changes as compared to the imported product. This indicated that the domestic products had more impurities with high concentration and the product quality was unstable. The study showed that the fluorescence fingerprint can be used as a novel method for quality control of chemical reagents.
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