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Updated: May 11, 2026
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PET/CT images of bilateral diffuse intraglomerular metastasis of malignant melanoma
Handan Tokmak1, Yasemin Ozlük, Nil Molinas Mandel
1American Hospital, Istanbul, Turkey. HandanT@amerikanhastanesi.org
Abstract:
Intraglomerular metastasis is a very rare condition with an underlying cause that is not yet well understood. We present the 18F-FDG PET/CT images of histologically proven intraglomerular metastases from newly diagnosed malignant melanoma with positive sentinel lymph node metastases. During the initial diagnostic evaluation period, the patient also had a sudden increased serum creatinine level. FDG PET/CT demonstrated diffuse glomerular FDG uptake unlike typical physiologic pelvicaliceal activity. Renal biopsy revealed diffuse crescentic lesions containing metastatic melanoma cells.
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