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15N CPMG Relaxation Dispersion for the Investigation of Protein Conformational Dynamics on the µs-ms Timescale
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ShereKhan--calculating exchange parameters in relaxation dispersion data from CPMG experiments

Adam Mazur1, Björn Hammesfahr, Christian Griesinger

  • 1Department of NMR-based Structural Biology, Max-Planck-Institute for Biophysical Chemistry, Am Fassberg 11, 37077 Göttingen, Germany.

Bioinformatics (Oxford, England)
|May 24, 2013
PubMed
Summary

This paper introduces a new tool called ShereKhan for analyzing NMR data related to biomolecular dynamics. The tool focuses on calculating exchange parameters from CPMG relaxation dispersion profiles. It provides a user-friendly web interface to make the analysis process easier for researchers. The tool is publicly available and includes documentation to help users. The study suggests that this approach may improve how scientists study molecular movements using NMR data. The authors propose that ShereKhan could help a wide range of researchers in biophysics and related fields.

Keywords:
NMR dynamics analysisCPMG data processingexchange parameter calculationbiomolecular motion analysis

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