Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Hypodermis01:02

Hypodermis

The hypodermis (the subcutaneous layer or superficial fascia) is present directly below the dermis. It connects the skin to the underlying fascia (fibrous tissue) of the bones and muscles. It is not strictly a part of the skin, although the border between the hypodermis and dermis can be difficult to distinguish. The hypodermis consists of well-vascularized, loose, areolar connective tissue and adipose tissue, which functions as a mode of fat storage and provides insulation and cushioning for...
Fats as Energy Storage Molecules01:06

Fats as Energy Storage Molecules

Triglycerides are a form of long-term energy storage molecules. They are made of glycerol and three fatty acids. To obtain energy from fat, triglycerides must first be broken down by hydrolysis into their two principal components, fatty acids and glycerol. This process, called lipolysis, takes place in the cytoplasm. The resulting fatty acids are oxidized by β-oxidation into acetyl-CoA, which is used by the Krebs cycle. The glycerol that is released from triglycerides after lipolysis directly...
Fats as Energy Storage Molecules01:06

Fats as Energy Storage Molecules

Triglycerides are a form of long-term energy storage molecules. They are made of glycerol and three fatty acids. To obtain energy from fat, triglycerides must first be broken down by hydrolysis into their two principal components, fatty acids and glycerol. This process, called lipolysis, takes place in the cytoplasm. The resulting fatty acids are oxidized by β-oxidation into acetyl-CoA, which is used by the Krebs cycle. The glycerol that is released from triglycerides after lipolysis directly...
Connective Tissue Cell Types01:22

Connective Tissue Cell Types

Connective tissue develops from the mesoderm of a developing embryo and consists of cells, fibers, and ground substance: a gel-like material containing large complexes of carbohydrates and proteins. Connective tissue was first identified as a separate tissue family in the 18th century, and Johannes Peter Muller coined the term connective tissue.
Fat cells (adipocytes), smooth muscle cells (myoblasts), and bone cells (osteoblasts) are some connective tissue cell types. Some immune system cells...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Pharmacological principles for safe benzodiazepine and Z-drug dose reduction.

Psychological medicine·2026
Same author

Benzodiazepine receptor agonist deprescribing principles for long-term use and dependence: modified Delphi recommendations from a multi-disciplinary expert panel.

Therapeutic advances in psychopharmacology·2026
Same author

Concerning the harm-benefit ratio of escitalopram for pediatric generalized anxiety disorder. A critical viewpoint on the evidence and approval process.

The International journal of risk & safety in medicine·2026
Same author

Stopping antidepressants safely.

African journal of primary health care & family medicine·2026
Same author

Supporting General Practitioners to Deprescribe Benzodiazepines and Z-Drugs in Primary Care: Findings From a Modified Delphi Study.

Basic & clinical pharmacology & toxicology·2026
Same author

Peak systolic velocity, not vein size, predicts abnormal sperm count in adolescent Tanner V patients with primary left varicocele.

Journal of pediatric urology·2026
Same journal

When LXA4 meets white fat: browning via the miR-133a-3p/SIRT1 pathway in mouse models.

Adipocyte·2026
Same journal

Twf1 regulates adipocyte proliferation and differentiation through Yap nucleus accumulation.

Adipocyte·2026
Same journal

Normalized periprostatic adipose tissue thickness: an imaging marker associated with prostate biopsy outcomes among patients with PI-RADS and PSA double gray zone.

Adipocyte·2026
Same journal

Multi-omics integration reveals convergent extracellular matrix remodelling and lipid metabolic reprogramming as central axes of adipocyte differentiation from mouse embryonic stem cells.

Adipocyte·2026
Same journal

Wt1 facilitates visceral beige fat formation to combat abdominal obesity.

Adipocyte·2026
Same journal

A non-invasive method for light-inducible knockout across all cell types in mouse subcutaneous adipose tissue.

Adipocyte·2026
See all related articles

Related Experiment Video

Updated: May 11, 2026

Identification and Dissection of Diverse Mouse Adipose Depots
06:31

Identification and Dissection of Diverse Mouse Adipose Depots

Published on: July 11, 2019

WAT is a functional adipocyte?

Christopher Church1, Mark Horowitz, Matthew Rodeheffer

  • 1Section of Comparative Medicine; Yale University; New Haven, CT USA.

Adipocyte
|May 24, 2013
PubMed
Summary
This summary is machine-generated.

Adipocytes store lipids, but other cells can too. Understanding lipid processing in all tissues is key to defining adipocytes and metabolic disease.

Keywords:
PPARcadipocyteadiponectinleptinlipidwhite adipose tissue

More Related Videos

Semi-Automated Isolation of the Stromal Vascular Fraction from Murine White Adipose Tissue Using a Tissue Dissociator
06:08

Semi-Automated Isolation of the Stromal Vascular Fraction from Murine White Adipose Tissue Using a Tissue Dissociator

Published on: May 19, 2023

Related Experiment Videos

Last Updated: May 11, 2026

Identification and Dissection of Diverse Mouse Adipose Depots
06:31

Identification and Dissection of Diverse Mouse Adipose Depots

Published on: July 11, 2019

Semi-Automated Isolation of the Stromal Vascular Fraction from Murine White Adipose Tissue Using a Tissue Dissociator
06:08

Semi-Automated Isolation of the Stromal Vascular Fraction from Murine White Adipose Tissue Using a Tissue Dissociator

Published on: May 19, 2023

Area of Science:

  • Biochemistry
  • Cell Biology
  • Metabolic Research

Background:

  • Adipose tissue, primarily composed of adipocytes, is the main site of lipid storage in vertebrates.
  • Adipocytes are specialized cells with roles in fuel storage, endocrine, nervous, and immune functions.
  • Lipid accumulation is not exclusive to adipocytes; ectopic lipid deposition occurs in non-adipose tissues like the liver, muscle, and heart.

Purpose of the Study:

  • To define the adipocyte by elucidating the necessary and sufficient lipid processing components for lipid accumulation.
  • To differentiate adipocyte-specific functions from general lipid handling mechanisms in non-adipose tissues.

Main Methods:

  • The abstract does not specify the methods used.
  • Further research is needed to determine the specific lipid processing components and their roles.

Main Results:

  • The abstract does not specify the results.
  • Ectopic lipid accumulation in non-adipose tissues, alongside excessive adipose tissue lipid accumulation, contributes to metabolic disease.

Conclusions:

  • A comprehensive understanding of lipid processing components is crucial for a clearer definition of the adipocyte.
  • Distinguishing adipocyte-specific functions from general lipid metabolism is essential for understanding and treating metabolic diseases.