Related Experiment Video
Updated: May 11, 2026
10:26
A Multicenter MRI Protocol for the Evaluation and Quantification of Deep Vein Thrombosis
Published on: June 2, 2015
Gadofosveset trisodium: abdominal and peripheral vascular applications
Amy Srur Sabach1, Mary Bruno, Danny Kim
1Department of Radiology, New York University Langone Medical Center, New York, NY, USA.
AJR. American Journal of Roentgenology
|May 25, 2013
Summary
Gadofosveset trisodium enhances MR angiography for abdominal and peripheral vascular disease. Its long intravascular residence time allows detailed evaluation of venous, dynamic, and functional vascular conditions with a single low dose.
Area of Science:
- Radiology and Medical Imaging
- Vascular Medicine
- Pharmacology
Background:
- Vascular diseases, including abdominal and peripheral conditions, require accurate diagnostic imaging.
- Magnetic Resonance Angiography (MRA) is a key imaging modality for vascular assessment.
- Contrast agents play a crucial role in enhancing MRA visualization.
Purpose of the Study:
- To review the diverse applications of gadofosveset trisodium in diagnosing abdominal and peripheral vascular diseases.
- To describe the fundamental properties, technical aspects, and current/future clinical uses of gadofosveset trisodium.
Main Methods:
- Review of existing literature on gadofosveset trisodium.
- Analysis of technical considerations for its use in MR angiography.
- Evaluation of clinical data and potential future applications.
Main Results:
- Gadofosveset trisodium enables comprehensive, high-resolution arterial and venous MR angiography.
- Its prolonged intravascular residence time is a key characteristic.
- Demonstrated utility in evaluating various vascular pathologies.
Conclusions:
- Gadofosveset trisodium is effective for detailed arterial and venous MR angiography.
- Its sustained presence in blood vessels makes it ideal for assessing venous, dynamic, and functional vascular diseases.
- A single, low-dose injection of gadofosveset trisodium can provide extensive vascular imaging information.
Related Concept Videos
01:16Local Anesthetics: Clinical Application as Intravenous Regional Anesthesia
Intravenous regional anesthesia or the Bier block technique is used to anesthetize a specific limb or extremity. It uses exsanguinated or blood-drained vessels to transport local anesthetics or LAs to the peripheral nerve trunks. Lidocaine without vasoconstrictors like epinephrine is most commonly used for this technique. Other drugs used are prilocaine, ropivacaine, and chloroprocaine. Bupivacaine is not recommended for this technique due to its high cardiac toxicity.
One of the advantages of...
One of the advantages of...
01:19Imaging Studies VII: Vascular Imaging
DefinitionRenal angiography, also known as renal arteriography, is an imaging technique used to obtain a comprehensive view of blood flow and the vascular structure of blood vessels in the kidneys and surrounding areas.PurposeRenal angiography detects blood vessel abnormalities in the kidneys, such as aneurysms, stenosis, thrombosis, vascular tumors, and renal artery stenosis. It evaluates kidney function and guides interventional treatments like angioplasty or stent placement.Pre-Procedure...
01:27Imaging Studies III: Computed Tomography
DefinitionComputed Tomography (CT) of the genitourinary (GU) tract is a non-invasive imaging modality that utilizes X-rays and computer processing to generate detailed cross-sectional images of the urinary system, encompassing the kidneys, ureters, bladder, and adjacent structures such as the adrenal glands.PurposeCT scans of the GU tract serve several diagnostic and therapeutic purposes, including:Diagnosis of Urinary Tract Diseases: Detects kidney stones, tumors, cysts, and congenital...
01:28Antihypertensive Drugs: Potassium-Sparing Diuretics
Liddle syndrome is a genetically inherited form of hypertension characterized by the overactivity of epithelial sodium channels in the nephron, the functional unit of the kidney. This heightened activity leads to increased sodium reabsorption and excessive excretion of potassium. To counteract this, potassium-sparing diuretics such as amiloride are used. They function by blocking these sodium channels, thereby reducing the influx of sodium into the epithelial cells and minimizing the loss of...
01:29Drug Delivery: Parenteral Route
The parenteral route is a critical method of drug administration. It delivers compounds directly into the systemic circulation and bypasses the gastrointestinal tract. This approach is particularly advantageous for drugs that exhibit poor absorption or instability when administered orally.
There are three primary parenteral routes: intravenous (IV), intramuscular (IM), and subcutaneous (SC). The IV route introduces the drug directly into the bloodstream, ensuring immediate action. The IM route...
There are three primary parenteral routes: intravenous (IV), intramuscular (IM), and subcutaneous (SC). The IV route introduces the drug directly into the bloodstream, ensuring immediate action. The IM route...
01:28Imaging Studies for Cardiovascular System V: CT
Cardiac computed tomography (CT) scanning is an advanced cardiac imaging technique that utilizes CT technology, with or without intravenous (IV) contrast, to produce accurate cross-sectional virtual slices of specific areas of the heart, coronary circulation, and major blood vessels such as the aorta, pulmonary veins, and arteries. The computer processes these slices to generate three-dimensional images. Multidetector CT (MDCT) is a rapid form of CT scanning that captures multiple slices...