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Related Concept Videos

Gap Junctions01:37

Gap Junctions

Multicellular organisms employ a variety of ways for cells to communicate with each other. Gap junctions are specialized proteins that form pores between neighboring cells in animals, connecting the cytoplasm between the two, and allowing for the exchange of molecules and ions. They are found in a wide range of invertebrate and vertebrate species, mediate numerous functions including cell differentiation and development, and are associated with numerous human diseases, including cardiac and...
Gap Junctions01:27

Gap Junctions

The cytoplasm of adjacent animal cells can exchange small molecules, ions, and secondary messengers via the communication channels which form the gap junctions. These junctions comprise a few hundred to thousands of molecular channels, each made of two halves, called the connexon hemichannel. A connexon is a hexamer of six transmembrane connexin proteins, which assemble radially, thus forming a pore or channel in the center. One connexon hemichannel docks with a corresponding connexon on the...
Metal-Semiconductor Junctions01:24

Metal-Semiconductor Junctions

The contact of metal and semiconductor can lead to the formation of a junction with either Schottky or Ohmic behavior.
Schottky Barriers
Schottky barriers arise when a metal with a work function (Φm) contacts a semiconductor with a different work function (Φs). Initially, electrons transfer until the Fermi levels of the metal and semiconductor align at equilibrium. For instance, if Φm > Φs, the semiconductor Fermi level is higher than the metal's before contact. The semiconductor's...
Tight Junctions01:29

Tight Junctions

Tight junctions are molecular seals between cells that prevent the leaking of fluids, ions, and other small solutes across cavities and compartments in multicellular organisms. They are mainly composed of claudin and occludin transmembrane proteins, and other proteins such as tricellulin and JAM (junctional adhesion molecule). All these proteins are 4-pass transmembrane proteins, except JAM, which is a single-pass transmembrane protein belonging to the immunoglobulin superfamily. The...
Mechanically-gated Ion Channels01:12

Mechanically-gated Ion Channels

Mechanically-gated ion channels are proteins found in eukaryotic and prokaryotic cell membranes that open in response to mechanical stress. Tension, compression, swelling, and shear stress can alter the conformation of the protein, opening a transmembrane channel that allows the passage of ions for signal transmission. In eukaryotes, mechanically-gated channels are distributed in several regions like the neurons, lungs, skin, bladder, and heart, where they play critical roles in numerous...
Mechanically-gated Ion Channels01:12

Mechanically-gated Ion Channels

Mechanically-gated ion channels are proteins found in eukaryotic and prokaryotic cell membranes that open in response to mechanical stress. Tension, compression, swelling, and shear stress can alter the conformation of the protein, opening a transmembrane channel that allows the passage of ions for signal transmission. In eukaryotes, mechanically-gated channels are distributed in several regions like the neurons, lungs, skin, bladder, and heart, where they play critical roles in numerous...

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Related Experiment Video

Updated: May 11, 2026

Nanofabrication of Gate-defined GaAs/AlGaAs Lateral Quantum Dots
15:47

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Published on: November 1, 2013

Three-terminal single-molecule junctions formed by mechanically controllable break junctions with side gating.

Dong Xiang1, Hyunhak Jeong, Dongku Kim

  • 1Department of Physics and Astronomy, Seoul National University, Seoul 151-747, Korea.

Nano Letters
|May 25, 2013
PubMed
Summary

Researchers developed a stable three-terminal molecular junction using mechanically controllable break junction (MCBJ) technology. A side-gate electrode precisely controls molecular conductance by altering electronic structure, enabling new single-molecule transistor designs.

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Area of Science:

  • Molecular electronics
  • Nanotechnology
  • Quantum transport

Background:

  • Molecules offer potential for miniaturized electronic devices due to their size and self-assembly properties.
  • A key challenge in molecule-based electronics is creating stable molecular junctions and controlling current flow.
  • Existing methods often struggle with junction reliability and precise electrical control.

Purpose of the Study:

  • To develop a stable, gate-tunable single-molecule junction for electronic devices.
  • To demonstrate precise control over molecular conductance using an external electric field.
  • To advance the design of mechanically stable single-molecule transistors.

Main Methods:

  • Fabrication of a three-terminal junction using the mechanically controllable break junction (MCBJ) technique.
  • Integration of a noncontact side-gate electrode positioned nanometers from the molecular junction.
  • Conductance measurements and ab initio calculations to analyze electronic structure modulation.

Main Results:

  • Successful formation of stable single-molecule junctions using MCBJ.
  • Demonstrated significant modulation of molecular conductance via the side-gate electrode.
  • Confirmed that the applied electric field alters the molecular electronic structure, impacting conductance.

Conclusions:

  • The developed three-terminal junction provides a stable platform for molecular electronics.
  • Side-gate control offers a novel method for tuning molecular conductance in electronic devices.
  • This approach paves the way for advanced mechanically stable single-molecule transistors.