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Related Concept Videos

Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy01:30

Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy

Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the colonic...
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Antiasthma Drugs: Mast Cell Stabilizers and Anti-IgE Drugs

Asthma is a chronic respiratory condition for which new therapeutic avenues, including anti-inflammatory drugs like mast cell stabilizers and anti-IgE treatments, continue to be developed.
Mast cell stabilizers, such as cromolyn (also known as sodium cromoglycate) and nedocromil (Tilade), are effective drugs in asthma management. These stabilizers hinder histamine release by skillfully obstructing the activation of mast cells and other cellular entities. Notably, they navigate this task without...
Allergic Reactions: Anaphylaxis01:30

Allergic Reactions: Anaphylaxis

Anaphylaxis is a severe, life-threatening hypersensitivity reaction mediated by Immunoglobulin E (IgE) antibodies. When IgE binds to allergens, it triggers the release of mediators– histamine, leukotrienes, and prostaglandins from mast cells and basophils. These mediators cause vasodilation, edema, and inflammation, leading to various symptoms.The primary allergens causing anaphylaxis include food items (e.g., peanuts, shellfish), drugs (e.g., penicillin, asparaginase, corticotropin, heparin),...
Allergic Reactions02:06

Allergic Reactions

Overview
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Allergic Drug Reactions

Allergic reactions related to drugs are hypersensitivity responses driven by the immune system and bear no connection to the drug's therapeutic action. While drugs in isolation do not trigger an immune response, they can interact with endogenous proteins to form antigens. These antigens stimulate lymphocytes to produce antibodies. IgE-type antibodies attach themselves to mast cells. Upon subsequent exposure to the same stimulus, the antigen-antibody interaction is initiated, unleashing numerous...
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Related Experiment Video

Updated: May 11, 2026

A Component-resolved Diagnostic Approach for a Study on Grass Pollen Allergens in Chinese Southerners with Allergic Rhinitis and/or Asthma
06:34

A Component-resolved Diagnostic Approach for a Study on Grass Pollen Allergens in Chinese Southerners with Allergic Rhinitis and/or Asthma

Published on: June 4, 2017

Dietary intervention for allergic disease.

Yi Huang, Guansong Wang, Changzheng Wang1

  • 1Institute of Respiratory Disease, Second Affiliated Hospital, Third Military Medical University, Chongqing, China. czwang@netease.com.

Current Pharmaceutical Design
|May 25, 2013
PubMed
Summary

Dietary factors influence allergic disease development, particularly in children. While promising, current evidence on dietary interventions is inconsistent, necessitating further research for personalized approaches.

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Basophil Activation Test for Allergy Diagnosis
07:22

Basophil Activation Test for Allergy Diagnosis

Published on: May 31, 2021

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Last Updated: May 11, 2026

A Component-resolved Diagnostic Approach for a Study on Grass Pollen Allergens in Chinese Southerners with Allergic Rhinitis and/or Asthma
06:34

A Component-resolved Diagnostic Approach for a Study on Grass Pollen Allergens in Chinese Southerners with Allergic Rhinitis and/or Asthma

Published on: June 4, 2017

Basophil Activation Test for Allergy Diagnosis
07:22

Basophil Activation Test for Allergy Diagnosis

Published on: May 31, 2021

Area of Science:

  • Allergy and Immunology
  • Nutritional Science
  • Epidemiology

Background:

  • Rising incidence of allergic diseases globally.
  • Dietary factors implicated in allergic disease development, especially in early childhood.
  • Immunological mechanisms provide a basis for dietary interventions.

Purpose of the Study:

  • To review the current evidence on dietary interventions for allergic diseases.
  • To address inconsistencies in randomized controlled trials (RCTs) and epidemiological findings.
  • To highlight the need for a multidisciplinary approach to understand dietary impacts.

Main Methods:

  • Review of epidemiological studies.
  • Analysis of immunological mechanisms.
  • Evaluation of randomized controlled trials (RCTs).

Main Results:

  • Inconsistencies exist between epidemiological, immunological, and RCT findings.
  • Dietary interventions show potential in specific populations.
  • The complexity of allergic disease pathogenesis complicates definitive conclusions.

Conclusions:

  • Dietary interventions for allergic diseases require further investigation.
  • Collaborative efforts among clinicians, epidemiologists, immunologists, and geneticists are crucial.
  • Identifying specific population subgroups for individualized dietary interventions is a key future direction.