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Updated: May 11, 2026

Prospecting Microbial Strains for Bioremediation and Probiotics Development for Metaorganism Research and Preservation
Published on: October 31, 2019
Alkaloids from the deep-sea-derived fungus Aspergillus westerdijkiae DFFSCS013
Jiang Peng1, Xiao-Yong Zhang, Zheng-Chao Tu
1Key Laboratory of Marine Bio-resources Sustainable Utilization/Guangdong Key Laboratory of Marine Material Medical/RNAM Center for Marine Microbiology, South China Sea Institute of Oceanology, Chinese Academy of Sciences, 164 West Xingang Road, Guangzhou, People's Republic of China.
Abstract:
Two new benzodiazepine alkaloids, circumdatins K and L (1, 2), two new prenylated indole alkaloids, 5-chlorosclerotiamide (3) and 10-epi-sclerotiamide (4), and one novel amide, aspergilliamide B (5), together with six known alkaloids were isolated from the deep-sea-derived fungus Aspergillus westerdijkiae DFFSCS013. Their structures were elucidated by extensive spectroscopic analysis. All of the compounds were tested for cytotoxicity toward human carcinoma A549, HL-60, K562, and MCF-7 cell lines.
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