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Related Concept Videos

Esophageal Strictures-I: Introduction01:30

Esophageal Strictures-I: Introduction

Esophageal strictures involve abnormal narrowing or tightening of the esophagus. They vary in length and severity, ranging from mild constriction to complete obstruction, and are classified as benign (noncancerous) or malignant (cancerous).
Etiology
The primary cause of esophageal strictures is long-standing gastroesophageal reflux disease (GERD), accounting for about 70 to 80% of adult cases. Chronic acid reflux can lead to injury and scarring of the esophageal lining, culminating in...
Pyloric Obstruction01:11

Pyloric Obstruction

Pyloric obstruction, also referred to as gastric outlet obstruction, is a condition characterized by narrowing or blockage at the pylorus—the muscular valve regulating the flow of stomach contents into the duodenum. When this passage becomes impaired, the stomach cannot effectively empty its contents into the small intestine. This disruption leads to a range of gastrointestinal symptoms, including early satiety, bloating, epigastric pain, postprandial nausea, persistent vomiting, and...
Peptic Ulcer Disease I: Introduction01:30

Peptic Ulcer Disease I: Introduction

Peptic Ulcer Disease (PUD) is characterized by mucosal excavation in the esophagus, stomach, pylorus, or duodenum. It can manifest as acute or chronic based on the extent and duration of mucosal involvement.
An acute ulcer, marked by superficial erosion and minimal inflammation, swiftly resolves upon identifying and addressing the underlying cause. In contrast, a chronic ulcer persists, potentially eroding through the muscular wall and forming fibrous tissue.
Peptic ulcers can also be...
Esophageal Strictures-II: Clinical Features and Management01:26

Esophageal Strictures-II: Clinical Features and Management

Patients with esophageal strictures often experience a range of symptoms. Initially, they may have difficulty swallowing solid foods, which can progress to include liquids. Additional symptoms may involve chest pain or discomfort, regurgitating food and fluids, heartburn, unintentional weight loss, coughing or choking during meals, and hoarseness.
Healthcare providers should gather a comprehensive medical history and conduct a physical examination for diagnosis. If esophageal stricture is...
Diverticular Disease of the Colon01:27

Diverticular Disease of the Colon

Diverticular disease involves the formation of diverticula—small sac-like outpouchings of the colonic wall—and their complications. It most commonly affects the sigmoid colon due to higher intraluminal pressure and structural vulnerability. It results from structural weakness and increased pressure in the colon, producing pseudodiverticula that may remain silent or progress to inflammation and serious complications.Structure of DiverticulaIn diverticulosis, these outpouchings are...
Inflammatory Bowel Disease V: Surgical Management01:21

Inflammatory Bowel Disease V: Surgical Management

Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:

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Author's reply: "ERCP for pediatric chronic pancreatitis: PEP prophylaxis and multidimensional outcome assessment deserve greater attention".

Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver·2026

Related Experiment Video

Updated: May 11, 2026

Laparoscopic Choledochal Cyst Excision and Roux-en-Y Choledochojejunostomy in Adults
04:14

Laparoscopic Choledochal Cyst Excision and Roux-en-Y Choledochojejunostomy in Adults

Published on: February 28, 2025

Does an isolated benign choledochal stricture hide a PSC?

Paola De Angelis1, Renato Tambucci, Erminia Romeo

  • 1Digestive Surgery and Endoscopy Unit, Bambino Gesù Children's Hospital, IRCCS, Rome. paoladeangelis.opbg@gmail.com

Journal of Pediatric Surgery
|May 25, 2013
PubMed
Summary
This summary is machine-generated.

Isolated benign choledochal strictures (IBCS) in children are rare but treatable with endoscopic retrograde cholangiopancreatography (ERCP). Some cases may indicate a link between IBCS and primary sclerosing cholangitis (PSC) or ulcerative colitis (UC).

Related Experiment Videos

Last Updated: May 11, 2026

Laparoscopic Choledochal Cyst Excision and Roux-en-Y Choledochojejunostomy in Adults
04:14

Laparoscopic Choledochal Cyst Excision and Roux-en-Y Choledochojejunostomy in Adults

Published on: February 28, 2025

Area of Science:

  • Pediatric Gastroenterology
  • Hepatology
  • Interventional Endoscopy

Background:

  • Extra-hepatic biliary tree strictures in children are uncommon, often stemming from benign inflammatory causes or idiopathic fibrosing pancreatitis.
  • Primary sclerosing cholangitis (PSC) can present as single or multiple biliary strictures.
  • This study focuses on isolated benign choledochal stricture (IBCS) in pediatric patients.

Purpose of the Study:

  • To describe the clinical presentation, treatment strategies, and outcomes for children diagnosed with IBCS.
  • To evaluate the efficacy of endoscopic retrograde cholangiopancreatography (ERCP) in managing IBCS.
  • To explore potential associations between IBCS and other inflammatory conditions like ulcerative colitis (UC) and PSC.

Main Methods:

  • Magnetic resonance cholangiography (MRC) for diagnosis in all six patients.
  • Diagnostic and therapeutic ERCP, including sphincterotomy, stricture dilation, and stenting, performed in five patients.
  • Intra-choledochal mini-probe endoscopic ultrasound (EUS) with biopsy in four patients; colonoscopy for suspected UC.

Main Results:

  • Six pediatric patients (mean age 12.1 years for males, 14.2 for females) with IBCS were identified.
  • Presentations included acute biliary pancreatitis, obstructive jaundice, cholestasis, and pancreatitis.
  • All patients were asymptomatic post-treatment (mean follow-up 21 months); however, four developed UC and one developed PSC.

Conclusions:

  • Therapeutic ERCP is an effective treatment for IBCS in children.
  • The development of UC in some patients suggests a potential link between IBCS and PSC, warranting further investigation.