Related Experiment Video
Updated: May 5, 2026
Processing of Primary Brain Tumor Tissue for Stem Cell Assays and Flow Sorting
Published on: September 25, 2012
Neuroblastoma: developmental biology, cancer genomics and immunotherapy
Nai-Kong V Cheung1, Michael A Dyer
1Department of Pediatrics, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA. cheungn@mskcc.org
Abstract:
Neuroblastoma is a solid tumour that arises from the developing sympathetic nervous system. Over the past decade, our understanding of this disease has advanced tremendously. The future challenge is to apply the knowledge gained to developing risk-based therapies and, ultimately, improving outcome. In this Review we discuss the key discoveries in the developmental biology, molecular genetics and immunology of neuroblastoma, as well as new translational tools for bringing these promising scientific advances into the clinic.
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