Correlation among the heart rate variability indices in healthy children and those with atrial septal defect

Bülent Koca1, Süleyman Bakari, Funda Oztunç

  • 1Department of Pediatric Cardiology, Harran University, Şanlıurfa, Turkey. bkoca78@yahoo.com

Insights

Time and frequency domain measures of heart rate variability (HRV) are correlated in healthy children and those with atrial septal defect (ASD). Some HRV indices are strongly correlated, suggesting they can be used interchangeably.

Area of Science:

  • Cardiology
  • Pediatric Medicine
  • Biomedical Engineering

Background:

  • Heart rate variability (HRV) is assessed using time and frequency domain analyses.
  • Current research often employs either time or frequency domain measures exclusively.
  • Understanding the correlation between these domains is crucial for comprehensive HRV assessment.

Purpose of the Study:

  • To investigate the correlation between time and frequency domain indices of HRV.
  • To compare HRV correlations in healthy children versus children with atrial septal defect (ASD).

Main Methods:

  • Analysis of 24-hour Holter ECG records from 60 children (32 healthy, 28 with ASD).
  • Calculation of time domain and frequency domain HRV measures.
  • Statistical computation of correlations within and between time and frequency domains.

Main Results:

  • A positive correlation was observed across most HRV measures.
  • The low-frequency (LF) to high-frequency (HF) ratio showed a negative correlation.
  • Correlation strength varied among different HRV indices.

Conclusions:

  • Time and frequency domain HRV measures are significantly correlated in both healthy children and ASD patients.
  • Certain HRV indices exhibit strong correlations, indicating potential interchangeability in clinical use.
Abstract

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