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Related Concept Videos

Treatment Resistant Cancers02:56

Treatment Resistant Cancers

Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...
Treatment Resistent Cancers02:56

Treatment Resistent Cancers

Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...
Cancer Therapies02:49

Cancer Therapies

Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
Cancer Therapies02:49

Cancer Therapies

Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
Combination Therapies and Personalized Medicine02:50

Combination Therapies and Personalized Medicine

Combining two or more treatment methods increases the life span of cancer patients while reducing damage to vital organs or tissue from the overuse of a single treatment. Combination therapy also targets different cancer-inducing pathways, thus reducing the chances of developing resistance to treatment.
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
Combination Therapies and Personalized Medicine02:50

Combination Therapies and Personalized Medicine

Combining two or more treatment methods increases the life span of cancer patients while reducing damage to vital organs or tissue from the overuse of a single treatment. Combination therapy also targets different cancer-inducing pathways, thus reducing the chances of developing resistance to treatment.
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...

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Global and Current Research Trends of Single-Cell Sequencing in Cancer: A Bibliometric and Visualization Study
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Roundtable--the changing oncology landscape: evolution or revolution?

Roy Beveridge1, John Fox, Susan A Higgins

  • 1McKesson Specialty Health, USA.

Journal of the National Comprehensive Cancer Network : JNCCN
|May 25, 2013
PubMed
Summary
This summary is machine-generated.

Navigating the complex oncology landscape requires addressing rising medical costs and adapting therapeutic decision-making. Experts discussed innovative strategies beyond traditional formularies to manage cancer care effectively.

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Area of Science:

  • Oncology
  • Health Economics
  • Healthcare Policy

Background:

  • The oncology landscape presents multifaceted challenges for all stakeholders, including policymakers, payers, clinicians, and patients.
  • Current economic instability exacerbates these challenges, with proposed solutions sometimes contributing to the problem.

Purpose of the Study:

  • To summarize a panel discussion at the NCCN 18th Annual Conference focused on the evolving oncology landscape.
  • To explore key issues impacting cancer care delivery and decision-making.

Main Methods:

  • A synopsis of a distinguished panel discussion.
  • Expert insights on critical issues in oncology.

Main Results:

  • Discussion highlighted the astronomical costs associated with medical care in oncology.
  • Emphasis was placed on the necessity for clinicians to consider options beyond standard formularies.
  • The panel addressed the complexities of therapeutic decision-making influenced by 'big data'.

Conclusions:

  • Adapting to the changing oncology landscape requires innovative approaches to cost management and treatment selection.
  • Integrating 'big data' into clinical practice necessitates careful consideration of therapeutic decision-making processes.
  • Collaboration among stakeholders is crucial for advancing the standard of cancer care amidst economic pressures.