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Spatial regulation of RhoC activity defines protrusion formation in migrating cells

Jose Javier Bravo-Cordero1, Ved P Sharma, Minna Roh-Johnson

  • 1Department of Anatomy and Structural Biology, Albert Einstein College of Medicine of Yeshiva University, Bronx, NY 10461, USA. jose-javier.bravo@einstein.yu.edu

Journal of Cell Science
|May 25, 2013
PubMed

Keywords:
Actin cytoskeletonChemotaxisDirectional protrusionRhoC GTPasep190RhoGAPp190RhoGEFcell migration mechanismsactin polymerization regulationRho GTPase signalingleading edge protrusion dynamics

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