Related Experiment Video
Updated: May 11, 2026

Heterotopic and Orthotopic Tracheal Transplantation in Mice used as Models to Study the Development of Obliterative Airway Disease
Published on: January 20, 2010
Tracheobronchopathia osteochondroplastica--a rare or an overlooked entity?
Shikha Jindal1, Alok Nath, Zafar Neyaz
1Department of Pulmonary Medicine, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India.
Tracheobronchopathia osteochondroplastica presents with airway nodules. This report details imaging findings to improve radiologist recognition of this underdiagnosed condition.
Area of Science:
- Pulmonology
- Radiology
- Pathology
Background:
- Tracheobronchopathia osteochondroplastica (TOC) is a rare, benign airway disease characterized by submucosal cartilaginous and osseous nodules.
- It affects the large airways, potentially causing symptoms like dyspnea, cough, and recurrent infections.
Observation:
- This report presents computed tomography (CT) and bronchoscopic findings in two newly diagnosed cases of TOC.
- The imaging characteristics highlight the focal or diffuse nature of the airway nodules.
Findings:
- CT scans revealed characteristic submucosal nodules along the cartilaginous rings of the tracheobronchial tree.
- Bronchoscopy confirmed the presence of these nodules, providing direct visualization of the airway pathology.
Implications:
- Increased radiologist awareness of TOC imaging findings can lead to earlier diagnosis.
- Familiarizing radiologists with TOC is crucial for recognizing this underreported condition and improving patient management.
Related Concept Videos
Chronic Obstructive Pulmonary Disease III: Chronic Bronchitis Features
Chronic Obstructive Pulmonary Disease-II: Pathophysiology
Chronic Inflammation
Chronic Obstructive Pulmonary Disease I: Introduction
Pneumothorax II: Pathophysiology
Chronic Obstructive Pulmonary Disease-I: Introduction
Chronic Obstructive Pulmonary Disease
Smoking is a primary risk factor for COPD, with over 80% of patients having a history of it. Patients typically experience progressive dyspnea or labored breathing, frequent coughing, and recurrent pulmonary infections. Many eventually succumb to respiratory failure, characterized by...
