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Lofgren's Syndrome-Acute Onset Sarcoidosis and Polyarthralgia: A Case Report
Chan Woo Byun1, Seung Nam Yang, Joon Shik Yoon
1Department of Physical Medicine and Rehabilitation, Korea University Guro Hospital, Seoul, Korea.
Abstract:
Lofgren's syndrome is an acute form of sarcoidosis characterized by erythema nodosum, bilateral hilar lymphadenopathy (BHL), and polyarthralgia or polyarthritis. This syndrome is common among Caucasians but rare in the Korean population. A 44-year-old woman was admitted to our hospital complaining of polyarthralgia. A chest radiograph revealed BHL and nodular shadows. Angiotensin-converting enzyme levels were within the normal range. Tissue biopsy from a mediastinum lymph node showed noncaseating granulomas. We diagnosed her with Lofgren's syndrome, an acute form of sarcoidosis.
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