Transapical extirpation of a left ventricular thrombus in Takotsubo cardiomyopathy

Ryo Suzuki1, Tomoaki Kudo, Hiroshi Kurazumi

  • 1Department of Surgery and Clinical Science, Division of Cardiac Surgery, Yamaguchi University Graduate School of Medicine, 1-1-1 Minami-Kogushi, Ube, Yamaguchi 755-8505, Japan.

Insights

Takotsubo cardiomyopathy can cause left ventricular thrombus, a rare complication. Mobile thrombi in these patients pose a significant risk of thromboembolism, necessitating prompt intervention.

Area of Science:

  • Cardiology
  • Cardiovascular Medicine

Background:

  • Takotsubo cardiomyopathy (TTC), also known as stress-induced cardiomyopathy, is characterized by transient left ventricular dysfunction.
  • While typically presenting with ST-segment elevation mimicking myocardial infarction, coronary angiography often reveals unobstructed coronary arteries.

Observation:

  • A 58-year-old Japanese female presented with symptoms suggestive of acute coronary syndrome.
  • Initial investigations including electrocardiogram (ECG) showed ST elevation, but coronary angiography revealed normal coronary arteries.
  • The patient was diagnosed with Takotsubo cardiomyopathy and a concomitant left ventricular thrombus.

Findings:

  • Despite anticoagulation therapy, the left ventricular thrombus demonstrated increased mobility and protrusion.
  • Surgical intervention via a trans-apical approach was performed to extirpate the left ventricular thrombus.
  • This case highlights the potential for thrombus formation and complications in Takotsubo cardiomyopathy.

Implications:

  • Left ventricular thrombus formation is an uncommon but serious complication of Takotsubo cardiomyopathy.
  • Mobile and protruding left ventricular thrombi in TTC patients represent a high risk for thromboembolic events.
  • Early recognition and management, potentially including surgical removal, are crucial for improving outcomes in such cases.

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