[The study on the specific eruptions of malignant lymphoma. I. Clinical, pathological and immunopathological...

We investigated 31 cases of cutaneous malignant lymphoma diagnosed by skin biopsy during about 11 years at the University of Tsukuba Hospital. The specific eruption was occurred in 17.7% of all malignant lymphomas at the hospital. The skin was primarily affected in 5.8% of all malignant lymphomas including Hodgkin disease, and in 6.9% excluding Hodgkin disease. We divided 31 cases into 3 groups; Group A is the primary cutaneous lymphoma, and Group B and C are the secondary cutaneous lymphoma. The skin lesions of Group B share the major part. On the other hand, that of Group C is minimal and transient. The differences between group A/B and group C were the high frequency of epidermotropism. The T cell dominance, the widespread eruption and the variety of the eruptions for one case in Group A/B. Group A differed from group B/C by the specific plaque, and from Group B by the high frequency of Pautrier's microabscess. B cell lymphomas did not show dermal-epidermotropism as well as epidermotropism.