Related Experiment Video
Updated: May 11, 2026

High-resolution Functional Magnetic Resonance Imaging Methods for Human Midbrain
Published on: May 10, 2012
High-resolution optically-detected magnetic resonance imaging in an ambient magnetic field
Songtham Ruangchaithaweesuk1, Vasudeva Chintamsetti, Li Yao
1Department of Chemistry, University of Houston, Houston, TX 77204, USA.
Abstract:
Magnetic resonance imaging (MRI) in an ultralow magnetic field usually has poor spatial resolution compared to its high-field counterpart. The concomitant field effect and low signal level are among the major causes that limit the spatial resolution. Here, we report a novel imaging method, a zoom-in scheme, to achieve a reasonably high spatial resolution of 0.6 mm x 0.6mm without suffering the concomitant field effect. This method involves multiple steps of spatial encoding with gradually increased spatial resolution but reduced field-of-view. This method takes advantage of the mobility of ultralow-field MRI and the large physical size of the ambient magnetic field. We also demonstrate the use of a unique gradient solenoid to improve the efficiency of optical detection with an atomic magnetometer. The enhanced filling factor improved the signal level and consequently facilitated an improved spatial resolution.
Related Concept Videos
Magnetic Resonance Imaging
Atomic Nuclei: Magnetic Resonance
Imaging Studies for Cardiovascular System IV: CMRI
Nuclear Magnetic Resonance (NMR): Overview
NMR spectroscopy generates a spectrum where the characteristic absorption frequencies of the sample are...
Imaging Studies IV: Magnetic Resonance Imaging
NMR Spectrometers: Resolution and Error Correction

