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Updated: May 11, 2026

Assessment of Child Anthropometry in a Large Epidemiologic Study
Published on: February 2, 2017
Cesarean section and the risk of overweight in grade 6 children
Liang Wang1, Arsham Alamian, Jodi Southerland
1Department of Biostatistics and Epidemiology, College of Public Health, East Tennessee State University, P.O. Box 70259, Johnson City, TN, 37614, USA, wangl2@etsu.edu.
Insights
Cesarean section delivery is linked to a doubled risk of overweight and obesity in 6th-grade children. This association varies by gender, with males showing higher risks for both conditions.
Area of Science:
- Pediatrics
- Public Health
- Epidemiology
Background:
- Childhood overweight and obesity are significant public health concerns.
- The mode of delivery, specifically cesarean section (C-section), is increasingly recognized as a potential factor influencing long-term child health.
- Understanding the association between C-section and childhood adiposity is crucial for developing targeted interventions.
Purpose of the Study:
- To investigate the relationship between cesarean section delivery and the risk of overweight and obesity in children at grade 6.
- To explore potential sex-based differences in this association.
Main Methods:
- Utilized data from the National Institute of Child Health and Human Development Study of Early Child Care and Youth Development (phases I–III).
- Included 917 children with complete data from 1991–2004.
- Employed multiple logistic regression analyses to adjust for confounding variables and assess the association between C-section and childhood overweight/obesity.
Main Results:
- Children delivered via C-section demonstrated approximately double the likelihood of being overweight (OR = 1.86) or obese (OR = 1.87) compared to vaginally delivered children.
- Male children born via C-section had increased risks for both overweight (OR = 1.78) and obesity (OR = 2.58).
- Female children born via C-section showed an increased risk for being overweight (OR = 1.99) but not obesity.
Conclusions:
- Cesarean section delivery is associated with an elevated risk of overweight and obesity in 6th-grade children.
- The observed relationship between C-section and childhood adiposity differs between male and female children.
- Further longitudinal research is recommended to elucidate the long-term impacts of delivery mode on childhood overweight risk.
Unlabelled:
We examined the relationship between cesarean section (C-section) and the risk of overweight and obesity in children in grade 6 (mean age, 11.92 years; standard deviation = 0.34). Data from phase I through phase III of the National Institute of Child Health and Human Development Study of Early Child Care and Youth Development were used. Children with complete data from 1991 through 2004 were included in this study (n = 917). Multiple logistic regression analyses were used to adjust for potential confounding and to evaluate the association of C-section and childhood overweight and obesity. Compared to children delivered vaginally, children delivered by C-section had approximately twice the likelihood of being overweight (odds ratio (OR) = 1.86, 95 % confidence interval (CI) = 1.27-2.73) or obese (OR = 1.87, 95 % CI = 1.19-2.95). However, when examined according to sex, males delivered by C-section had an increased risk for being overweight (OR = 1.78, 95 % CI = 1.01-3.12) and obese (OR = 2.58, 95 % CI = 1.36-4.88), while females had an increased risk only for being overweight (OR = 1.99, 95 % CI = 1.17-3.39).
Conclusion:
C-section was associated with an increased risk of overweight and obesity in children in grade 6, but the relationship differed according to gender. Further longitudinal studies are warranted to examine the long-term effect of delivery mode on the risk of childhood overweight.
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