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Updated: May 11, 2026

Using the GAL4-UAS System for Functional Genetics in Anopheles gambiae
Published on: April 15, 2021
The evolution of the Anopheles 16 genomes project
Daniel E Neafsey1, George K Christophides, Frank H Collins
1Broad Institute, Cambridge, Massachusetts 02142, USA. neafsey@broadinstitute.org
Abstract:
We report the imminent completion of a set of reference genome assemblies for 16 species of Anopheles mosquitoes. In addition to providing a generally useful resource for comparative genomic analyses, these genome sequences will greatly facilitate exploration of the capacity exhibited by some Anopheline mosquito species to serve as vectors for malaria parasites. A community analysis project will commence soon to perform a thorough comparative genomic investigation of these newly sequenced genomes. Completion of this project via the use of short next-generation sequence reads required innovation in both the bioinformatic and laboratory realms, and the resulting knowledge gained could prove useful for genome sequencing projects targeting other unconventional genomes.
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