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Related Concept Videos

Synthetic Biology02:55

Synthetic Biology

Synthetic biology is an interdisciplinary science that involves using principles from disciplines such as engineering, molecular biology, cell biology, and systems biology. It involves remodeling existing organisms from nature or constructing completely new synthetic organisms for applications such as protein or enzyme production, bioremediation, value-added macromolecule production, and the addition of desirable traits to crops, to name a few.
Golden rice
Golden rice is a genetically modified...
Genome Annotation and Assembly03:36

Genome Annotation and Assembly

The genome refers to all of the genetic material in an organism. It can range from a few million base pairs in microbial cells to several billion base pairs in many eukaryotic organisms. Genome assembly refers to the process of taking the DNA sequencing data and putting it all back together in a correct order to create a close representation of the original genome. This is followed by the identification of functional elements on the newly assembled genome, a process called genome annotation.
Evolutionary Relationships through Genome Comparisons02:54

Evolutionary Relationships through Genome Comparisons

Genome comparison is one of the excellent ways to interpret the evolutionary relationships between organisms. The basic principle of genome comparison is that if two species share a common feature, it is likely encoded by the DNA sequence conserved between both species. The advent of genome sequencing technologies in the late 20th century enabled scientists to understand the concept of conservation of domains between species and helped them to deduce evolutionary relationships across diverse...

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Related Experiment Video

Updated: May 11, 2026

Automated Robotic Liquid Handling Assembly of Modular DNA Devices
11:22

Automated Robotic Liquid Handling Assembly of Modular DNA Devices

Published on: December 1, 2017

Emerging tools for synthetic genome design.

Bo-Rahm Lee1, Suhyung Cho, Yoseb Song

  • 1Intelligent Synthetic Biology Center, Daejeon, 305-701, Korea.

Molecules and Cells
|May 28, 2013
PubMed
Summary
This summary is machine-generated.

Synthetic biology enables the creation of predictable biological systems for applications like drug development and green fuels. Advances in DNA technologies are accelerating the engineering of these novel biological systems.

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Area of Science:

  • Synthetic biology
  • Biological engineering
  • Systems biology

Background:

  • Synthetic biology is an emerging field focused on designing and constructing new biological parts, devices, and systems.
  • Advances in DNA sequencing, synthesis, and editing have significantly improved the ability to engineer biological systems.
  • These engineered systems hold promise for various applications, including medicine, energy, and materials science.

Purpose of the Study:

  • To review emerging technologies and methodologies in synthetic biology for building designed biological systems.
  • To discuss the future perspectives and potential impact of synthetic biology.

Main Methods:

  • Review of recent advancements in DNA sequencing technologies.
  • Analysis of novel DNA synthesis platforms.
  • Evaluation of DNA editing tools and their applications in biological engineering.
  • Exploration of computational tools for biological system design.

Main Results:

  • Significant progress has been made in engineering predictable biological systems.
  • Key enabling technologies include high-throughput DNA sequencing, synthesis, and precise genome editing.
  • Emerging methodologies facilitate the rapid design, construction, and testing of biological systems.

Conclusions:

  • Synthetic biology is rapidly advancing, driven by technological innovations.
  • The field offers transformative potential for developing cheaper drugs, green fuels, biodegradable plastics, and targeted cancer therapies.
  • Continued development of enabling technologies will further expand the capabilities and applications of synthetic biology.